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Transferrin Receptor 抗体 (APC)

TFRC 适用: 人 FACS 宿主: 小鼠 Monoclonal MEM-75 APC
产品编号 ABIN238474
发货至: 中国
  • 抗原 See all Transferrin Receptor (TFRC) 抗体
    Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))
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    小鼠
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    单克隆
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    This Transferrin Receptor antibody is conjugated to APC
    应用范围
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    Flow Cytometry (FACS)
    交叉反应 (详细)
    Species reactivity (tested):Human
    纯化方法
    Size-exclusion chromatography
    免疫原
    NALM-6 human pre-B cell line
    克隆位点
    MEM-75
    亚型
    IgG1
    Top Product
    Discover our top product TFRC Primary Antibody
  • 应用备注
    Suitable for Flow Cytometry analysis of human blood cells using 10 m l reagent / 100 m l of whole blood or 10^6 cells in a suspension.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 15 mM sodium azide as preservative and 0.2 % (w/v) high-grade BSA (Protease free) as stabilizer
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store the antibody in the dark at 2-8 °C. Do Not Freeze! Avoid prolonged exposure to light.
    Shelf Life: one year from despatch.
    有效期
    12 months
  • 抗原
    Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))
    别名
    CD71 / TFRC (TFRC 产品)
    别名
    Trfr antibody, LOC100219280 antibody, tfr antibody, cd71 antibody, tfr1 antibody, trfr antibody, CD71 antibody, T9 antibody, TFR antibody, TFR1 antibody, TR antibody, TRFR antibody, p90 antibody, 2610028K12Rik antibody, AI195355 antibody, AI426448 antibody, AU015758 antibody, E430033M20Rik antibody, Mtvr-1 antibody, Mtvr1 antibody, transferrin receptor antibody, TFRC antibody, Tfrc antibody, tfrc antibody
    背景
    CD71 (transferrin receptor) is a type II transmembrane glycoprotein expressed as homodimer in erythroid blood cell line and in activated leukocytes. Upon binding of holotransferrin (complex of transferrin and iron ions), CD71 is internalized by clathrin-mediated endocytosis. Acidification of endosomes by vesicular membrane proton pumps leads to dissociation of iron ions, whereas transferrin (apotransferrin) remains associated with CD71 and recycles to the cell surface, where it is released upon exposure to normal pH . CD71 is also involved in uptake of non-transferrin bound iron.Synonyms: TfR1, Transferrin receptor protein 1, p90
    UniProt
    P02786
    途径
    Transition Metal Ion Homeostasis
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