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CD14 抗体 (APC)

CD14 适用: 人, 猴 FACS 宿主: 小鼠 Monoclonal MEM-18 APC
产品编号 ABIN238454
发货至: 中国
  • 抗原 See all CD14 抗体
    CD14
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    小鼠
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    This CD14 antibody is conjugated to APC
    应用范围
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    Flow Cytometry (FACS)
    交叉反应 (详细)
    Species reactivity (tested):Human, Non-Human Primates
    纯化方法
    Size-exclusion chromatography
    免疫原
    A crude mixture of human urinary proteins precipitated by ammonium sulphate from the urine of a patient suffering from proteinuria
    克隆位点
    MEM-18
    亚型
    IgG1
    Top Product
    Discover our top product CD14 Primary Antibody
  • 应用备注
    Suitable for Flow Cytometry analysis of human blood cells using 10 m l reagent / 100 m l of whole blood or 10^6 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS, pH 7.4 with 15 mM sodium azide as preservative and 0.2 % (w/v) high-grade BSA (protease free) as a stabilizer
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store the antibody in the dark at 2-8 °C. Do Not freeze! Avoid prolonged exposure to light.
    Shelf Life: One year from despatch.
    有效期
    12 months
  • 抗原
    CD14
    别名
    CD14 (CD14 产品)
    别名
    CD14 molecule antibody, CD14 antigen antibody, CD14 antibody, Cd14 antibody
    背景
    CD14 is a 55 kDa GPI-anchored glycoprotein, constitutively expressed on the surface of mature monocytes, macrophages, and neutrophils, where serves as a multifunctional lipopolysaccharide receptor, it is also released to the serum both as a secreted and enzymatically cleaved GPI-anchored form. CD14 binds lipopolysaccharide molecule in a reaction catalyzed by lipo-polysaccharide-binding protein (LBP), an acute phase serum protein. The soluble sCD14 is able to discriminate slight structural differences between lipopolysaccharides and is important for neutralization of serum allochthonous lipo-polysaccharides by reconstituted lipoprotein particles. CD14 affects allergic, inflammatory and infectious processes.Synonyms: Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein
    UniProt
    P08571
    途径
    TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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