CD14 抗体 (APC)
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- 抗原 See all CD14 抗体
- CD14
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适用
- 人, 猴
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CD14 antibody is conjugated to APC
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应用范围
- Flow Cytometry (FACS)
- 交叉反应 (详细)
- Species reactivity (tested):Human, Non-Human Primates
- 纯化方法
- Size-exclusion chromatography
- 免疫原
- A crude mixture of human urinary proteins precipitated by ammonium sulphate from the urine of a patient suffering from proteinuria
- 克隆位点
- MEM-18
- 亚型
- IgG1
- Top Product
- Discover our top product CD14 Primary Antibody
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- 应用备注
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Suitable for Flow Cytometry analysis of human blood cells using 10 m l reagent / 100 m l of whole blood or 10^6 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 缓冲液
- PBS, pH 7.4 with 15 mM sodium azide as preservative and 0.2 % (w/v) high-grade BSA (protease free) as a stabilizer
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
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Store the antibody in the dark at 2-8 °C. Do Not freeze! Avoid prolonged exposure to light.
Shelf Life: One year from despatch. - 有效期
- 12 months
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- 抗原
- CD14
- 别名
- CD14 (CD14 产品)
- 别名
- CD14 molecule antibody, CD14 antigen antibody, CD14 antibody, Cd14 antibody
- 背景
- CD14 is a 55 kDa GPI-anchored glycoprotein, constitutively expressed on the surface of mature monocytes, macrophages, and neutrophils, where serves as a multifunctional lipopolysaccharide receptor, it is also released to the serum both as a secreted and enzymatically cleaved GPI-anchored form. CD14 binds lipopolysaccharide molecule in a reaction catalyzed by lipo-polysaccharide-binding protein (LBP), an acute phase serum protein. The soluble sCD14 is able to discriminate slight structural differences between lipopolysaccharides and is important for neutralization of serum allochthonous lipo-polysaccharides by reconstituted lipoprotein particles. CD14 affects allergic, inflammatory and infectious processes.Synonyms: Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein
- UniProt
- P08571
- 途径
- TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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