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PIN1 抗体 (Internal Region)

PIN1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN233831
发货至: 中国
  • 抗原 See all PIN1 抗体
    PIN1 (Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 (PIN1))
    抗原表位
    • 15
    • 15
    • 11
    • 10
    • 8
    • 8
    • 6
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 110
    • 53
    • 39
    • 10
    • 9
    • 6
    • 6
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    宿主
    • 101
    • 13
    • 2
    • 1
    克隆类型
    • 104
    • 13
    多克隆
    标记
    • 58
    • 13
    • 12
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PIN1 antibody is un-conjugated
    应用范围
    • 86
    • 47
    • 40
    • 30
    • 20
    • 18
    • 14
    • 13
    • 13
    • 12
    • 5
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB), ELISA
    交叉反应
    犬, 绵羊, 猴
    产品特性
    Concentration Definition: by UV absorbance at 280 nm
    免疫原
    This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an sequence of human Pin1.
    亚型
    IgG
    Top Product
    Discover our top product PIN1 Primary Antibody
  • 应用备注
    This affinity purified antibody has been tested for use in ELISA and western blotting. Specific conditions for reactivity should be optimized by the end user.  Expect a band approximately 18 kDa in size corresponding to Pin1 by western blotting in the appropriate cell lysate or extract.  Lysates from 3T3, Jurkat, 293 or HeLa cells, as well as HeLa nuclear extract, are recommended for use as positive controls.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1.2 mg/mL
    缓冲液
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
  • Lucchetti, Caligiuri, Toffoli, Giordano, Rizzolio: "The prolyl isomerase Pin1 acts synergistically with CDK2 to regulate the basal activity of estrogen receptor α in breast cancer." in: PLoS ONE, Vol. 8, Issue 2, pp. e55355, (2013) (PubMed).

    La Montagna, Caligiuri, Maranta, Lucchetti, Esposito, Paggi, Toffoli, Rizzolio, Giordano: "Androgen receptor serine 81 mediates Pin1 interaction and activity." in: Cell cycle (Georgetown, Tex.), Vol. 11, Issue 18, pp. 3415-20, (2013) (PubMed).

    Rizzolio, Lucchetti, Caligiuri, Marchesi, Caputo, Klein-Szanto, Bagella, Castronovo, Giordano: "Retinoblastoma tumor-suppressor protein phosphorylation and inactivation depend on direct interaction with Pin1." in: Cell death and differentiation, Vol. 19, Issue 7, pp. 1152-61, (2012) (PubMed).

  • 抗原
    PIN1 (Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 (PIN1))
    别名
    PIN1 (PIN1 产品)
    别名
    DOD antibody, UBL5 antibody, dod antibody, ubl5 antibody, pin1 antibody, pin1a antibody, 0610025L01Rik antibody, D9Bwg1161e antibody, pin1b antibody, zgc:73206 antibody, PPIase pin1 antibody, MdPin1 antibody, Pin1 antibody, peptidylprolyl cis/trans isomerase, NIMA-interacting 1 antibody, peptidylprolyl cis/trans isomerase, NIMA-interacting 1 S homeolog antibody, protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1 antibody, peptidylprolyl cis/trans isomerase, NIMA-interacting 1 L homeolog antibody, peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 antibody, peptidyl-prolyl cis-trans isomerase Pin1 antibody, PIN1 antibody, Pin1 antibody, pin1 antibody, pin1.S antibody, pin1.L antibody, ppiD antibody, PITG_11123 antibody, LOC103419188 antibody
    背景
    Pin1 (peptidylprolyl cis/trans isomerase NIMA-interacting 1 protein) is an essential peptidylprolyl isomerase that regulates mitosis, presumably by interacting with NIMA and attenuating its mitosis-promoting activity.  Pin1 displays a preference for an acidic residue N-terminal to the isomerized proline bond and also catalyzes pSer/Thr-Pro cis/trans isomerizations.  Pin1 shows a nuclear localization.
    Synonyms: Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 antibody, Prolyl isomerase antibody, Protein (peptidylprolyl cis/trans isomerase) NIMA interacting 1 antibody, Protein NIMA interacting 1 antibody, Rotamase Pin1 antibody, UBL 5 antibody
    基因ID
    5300, 5453898
    UniProt
    Q13526
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