(2 references)-
- 抗原 See all PLVAP 抗体
- PLVAP (Plasmalemma Vesicle Associated Protein (PLVAP))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This PLVAP antibody is conjugated to FITC
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应用范围
- Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF)
- 过滤
- 0.2 μm filtered
- 克隆位点
- 174-2
- Top Product
- Discover our top product PLVAP Primary Antibody
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anti-Plasmalemma Vesicle Associated Protein (PLVAP) (AA 123-393) antibody
PLVAP 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Plasmalemma Vesicle Associated Protein (PLVAP) (AA 51-150) antibodyPLVAP 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Plasmalemma Vesicle Associated Protein (PLVAP) (AA 203-442) antibodyPLVAP 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Plasmalemma Vesicle Associated Protein (PLVAP) (AA 63-442) antibodyPLVAP 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Plasmalemma Vesicle Associated Protein (PLVAP) (AA 214-242) antibodyPLVAP 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB17891 unconjugated
anti-Plasmalemma Vesicle Associated Protein (PLVAP) (AA 221-250), (Middle Region) antibodyPLVAP 适用: 人 WB, FACS, EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- For immunohistology, flow cytometry, immunofluorescence and Western blotting, dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50.
- 限制
- 仅限研究用
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- 缓冲液
- PBS, containing 1 % bovine serum albumin and 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Product should be stored at 4 °C. Under recommended storage conditions, product is stable for one year.
- 有效期
- 12 months
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: "Molecular identification of PAL-E, a widely used endothelial-cell marker." in: Blood, Vol. 106, Issue 10, pp. 3405-9, (2005) (PubMed).
: "Plasmalemmal vesicle associated protein-1 is a novel marker implicated in brain tumor angiogenesis." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 11, Issue 21, pp. 7643-50, (2005) (PubMed).
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: "Molecular identification of PAL-E, a widely used endothelial-cell marker." in: Blood, Vol. 106, Issue 10, pp. 3405-9, (2005) (PubMed).
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- 抗原
- PLVAP (Plasmalemma Vesicle Associated Protein (PLVAP))
- 别名
- Plasmalemma Vesicle Associated Protein (PLVAP 产品)
- 别名
- MECA32 antibody, Pv1 antibody, FELS antibody, PV-1 antibody, PV1 antibody, gp68 antibody, plasmalemma vesicle associated protein antibody, Plvap antibody, PLVAP antibody
- 背景
- The monoclonal antibody 174/2 reacts with human plasmalemma vesicle associated protein (PLVAP), also known as PV1, PAL-E and FELS. PLVAP is a 60 kDa type II transmembrane glycoprotein which tends to form homodimers. PLVAP is widely expressed in the vasculature of normal tissues. The vascular staining pattern of PLVAP is quite unique among the endothelial cell antigens, since expression of other antigens (like ICAM-1, P-selectin, E-selectin or VCAM-1) is not limited to vascular endothelial cells. PLVAP expression in the vascular endothelial cells of the CNS is lost in association with formation of an intact blood-brain barrier. However, in the endothelium of human brain tumors expression of PLVAP is specifically up-regulated, making it a suitable antiangiogenic target for brain tumor therapy and cerebral edema. Furthermore, PLVAP is expressed in the vasculature of most other human tumors and as such useful as marker for tumor angiogenesis.
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