Ficolin 2 抗体
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- 抗原 See all Ficolin 2 (FCN2) 抗体
- Ficolin 2 (FCN2) (Ficolin (Collagen/fibrinogen Domain Containing Lectin) 2 (Hucolin) (FCN2))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Ficolin 2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoassay (IA)
- 交叉反应 (详细)
- Cross reactivity: Rat : Yes
- 过滤
- 0.2 μm filtered
- 克隆位点
- GN4
- 亚型
- IgG1
- Top Product
- Discover our top product FCN2 Primary Antibody
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- 应用备注
- For immunohistochemistry, immunoprecipitation and immuno assays, dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50.
- 限制
- 仅限研究用
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- 缓冲液
- PBS, containing 0.1 % bovine serum albumin and 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Product should be stored at 4 °C. Under recommended storage conditions, product is stable for at least one year. The exact expiry date is indicated on the label.
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Activation of the lectin complement pathway by H-ficolin (Hakata antigen)." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 168, Issue 7, pp. 3502-6, (2002) (PubMed).
: "Activation of the lectin complement pathway by ficolins." in: International immunopharmacology, Vol. 1, Issue 3, pp. 359-63, (2001) (PubMed).
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Activation of the lectin complement pathway by H-ficolin (Hakata antigen)." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 168, Issue 7, pp. 3502-6, (2002) (PubMed).
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- 抗原
- Ficolin 2 (FCN2) (Ficolin (Collagen/fibrinogen Domain Containing Lectin) 2 (Hucolin) (FCN2))
- 别名
- Ficolin-2 (FCN2 产品)
- 别名
- EBP-37 antibody, FCNL antibody, P35 antibody, ficolin-2 antibody, Fcn2 antibody, FCN1 antibody, fcn2 antibody, fcn2.S antibody, ficolin 2 antibody, ficolin B antibody, ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin) antibody, ficolin 2 L homeolog antibody, FCN2 antibody, Fcnb antibody, fcn2.L antibody
- 背景
- The monoclonal antibody GN4 recognizes human Ficolin-2, also known as L-ficolin. Ficolins are a family of pattern recognition molecules containing both a collagen-like domain and a fibrinogen-like domain that are capable of activating the complement system, through association with MASPs, on the surface of microorganisms. In human, three Ficolins are known: Ficolin-1 (M-ficolin), Ficolin-2 (L-ficolin), and Ficolin-3 (H-ficolin). Ficolin-1, is mainly expressed by monocytes, granulocytes and lung cells and is present locally in areas of inflammation. Ficolin-2 (also L-ficolin, ficolin L, EBP-37 or hucolin) is produced primarily by the liver. The association between Ficolin-2 and MASPs/sMAP is Ca2+-dependent. MASPs in Ficolin-2 - MASP complexes have proteolytic activities for C4, C2 and C3. Ficolin-2 also shows opsonic activity. Aliases Ficolin-2/P35, L-ficolin, ficolin L, EBP-37 or hucolin
- 途径
- Complement System
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