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CXCL10 抗体 (Biotin)

CXCL10 适用: 人 WB, FACS, IHC (fro), IA 宿主: 小鼠 Monoclonal 6D4 Biotin
产品编号 ABIN2191897
发货至: 中国
  • 抗原 See all CXCL10 抗体
    CXCL10 (Chemokine (C-X-C Motif) Ligand 10 (CXCL10))
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    小鼠
    克隆类型
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    单克隆
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    This CXCL10 antibody is conjugated to Biotin
    应用范围
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    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoassay (IA)
    过滤
    0.2 μm filtered
    克隆位点
    6D4
    Top Product
    Discover our top product CXCL10 Primary Antibody
  • 应用备注
    For immunohistochemistry, flow cytometry and Western blotting, dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50. Positive Acitvated plasmacytoid dendritic cells control Negative Normal liver control 1
    限制
    仅限研究用
  • 缓冲液
    PBS, containing 0.1 % bovine serum albumin and 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Product should be stored at 4 °C. Under recommended storage conditions, product is stable for at least one year. The exact expiry date is indicated on the label.
  • Curbishley, Eksteen, Gladue, Lalor, Adams: "CXCR 3 activation promotes lymphocyte transendothelial migration across human hepatic endothelium under fluid flow." in: The American journal of pathology, Vol. 167, Issue 3, pp. 887-99, (2005) (PubMed).

    Giustizieri, Albanesi, Scarponi, De Pità, Girolomoni: "Nitric oxide donors suppress chemokine production by keratinocytes in vitro and in vivo." in: The American journal of pathology, Vol. 161, Issue 4, pp. 1409-18, (2002) (PubMed).

    Hamamdzic, Phillips-Dorsett, Altman-Hamamdzic, London, London: "Reovirus triggers cell type-specific proinflammatory responses dependent on the autocrine action of IFN-beta." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 280, Issue 1, pp. L18-29, (2001) (PubMed).

  • 抗原
    CXCL10 (Chemokine (C-X-C Motif) Ligand 10 (CXCL10))
    别名
    C-X-C Motif Chemokine 10 (CXCL10 产品)
    别名
    CXCL10 antibody, C7 antibody, IFI10 antibody, INP10 antibody, IP-10 antibody, SCYB10 antibody, crg-2 antibody, gIP-10 antibody, mob-1 antibody, CRG-2 antibody, IP10 antibody, Ifi10 antibody, Scyb10 antibody, C-X-C motif chemokine ligand 10 antibody, C-X-C motif chemokine 10 antibody, chemokine (C-X-C motif) ligand 10 antibody, CXCL10 antibody, cxl10 antibody, Cxcl10 antibody
    背景
    The monoclonal antibody 6D4 recognizes human C-X-C motif chemokine 10 (IP-10), a protein of 98 amino acids. IP-10, also known as CXCL10, functions as ligand for the CXCR3 receptor. IP-10 belongs to the α-chemokine (C-X-C) family, which can be divided in two subfamilies: (1) potent chemoattractants for neutrophils, like IL-8 and (2) potent chemoattractants for lymphocytes, like the IFNγ inducible protein (IP)-10. IP-10 is produced by a wide variety of cell types ranging from neutrophils, dendritic cells and monocytes to hepatocytes, endothelial cells and keratinocytes. The cytokine is reported to be involved in a scala of inflammatory pathologies such as HIV, encephalitis, cutaneous T cell lymphoma, chronic hepatitis, psoriasis and acute anterior uveitis. Various observations strongly suggest a role for the C-X-C chemokines IL-8 and IP-10 in the regulation of angiogenic activity in cancer and in idiopathic pulmonary fibrosis. Furthermore IP-10 is associated with acute rejection processes estimated by the predictive properties of urinary IP-10 expression for the short- and long-term graft function after kidney transplantation. Aliases 10 kDa interferon gamma-induced protein, CXCL10, Small-inducible cytokine B10 Immunogen Recombinant human IP-10
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