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- 抗原 See all FABP3 抗体
- FABP3 (Fatty Acid Binding Protein 3, Muscle and Heart (FABP3))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This FABP3 antibody is conjugated to Biotin
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应用范围
- Western Blotting (WB), Immunoprecipitation (IP), Immunoassay (IA)
- 交叉反应 (详细)
- Cross reactivity: Rat H-FABP : Yes, Mouse H-FABP : Yes, Human B-FABP Average (in ELISA) Human I-FABP : No, Human A-FABP : No, Human L-FABP : No
- 过滤
- 0.2 μm filtered
- 克隆位点
- 67D3
- 亚型
- IgG1
- Top Product
- Discover our top product FABP3 Primary Antibody
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- 应用备注
- For Western blotting, dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50. Positive Heart cells, recombinant human H-FABP control 1
- 限制
- 仅限研究用
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- 缓冲液
- PBS, containing 0.1 % bovine serum albumin and 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Product should be stored at 4 °C. Under recommended storage conditions, product is stable for at least one year. The exact expiry date is indicated on the label.
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Quantification of heart fatty acid binding protein as a biomarker for drug-induced cardiac and musculoskeletal necroses." in: Proteomics. Clinical applications, Vol. 1, Issue 7, pp. 661-71, (2010) (PubMed).
: "Brain- and heart-type fatty acid-binding proteins in the brain: tissue distribution and clinical utility." in: Clinical chemistry, Vol. 50, Issue 9, pp. 1568-75, (2004) (PubMed).
: "Monoclonal antibodies to human heart fatty acid-binding protein." in: Journal of immunological methods, Vol. 183, Issue 1, pp. 149-53, (1995) (PubMed).
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Quantification of heart fatty acid binding protein as a biomarker for drug-induced cardiac and musculoskeletal necroses." in: Proteomics. Clinical applications, Vol. 1, Issue 7, pp. 661-71, (2010) (PubMed).
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- 抗原
- FABP3 (Fatty Acid Binding Protein 3, Muscle and Heart (FABP3))
- 别名
- Fatty Acid-Binding Protein, Heart (FABP3 产品)
- 别名
- Fabph-1 antibody, Fabph-4 antibody, Fabph1 antibody, Fabph4 antibody, H-FABP antibody, Mdgi antibody, FABP11 antibody, M-FABP antibody, MDGI antibody, O-FABP antibody, FABP antibody, FABP-3 antibody, fabp3 antibody, fatty acid binding protein 3 antibody, fatty acid binding protein 3, muscle and heart antibody, FABP3 antibody, Fabp3 antibody, fabp3 antibody
- 背景
- The monoclonal antibody 67D3 recognizes human heart-type fatty acid-binding protein (H-FABP) of both natural and recombinant origin. The H-FABP protein is derived from the human FABP3 gene. FABPs are small intracellular proteins (~13-14 kDa) with a high degree of tissue specificity that bind long chain fatty acids. They are abundantly present in various cell types and play an important role in the intracellular utilization of fatty acids, transport and metabolism. There are at least nine distinct types of FABP, each showing a specific pattern of tissue expression. Due to its small size, FABP leaks rapidly out of ischemically damaged necrotic cells leading to a rise in serum levels. Ischemically damaged tissues are characterized histologically by absence (or low presence) of FABP facilitating recognition of such areas. H-FABP is localized in the heart, skeletal and smooth muscle, mammary epithelial cells, aorta, distal tubules of the kidney, lung, brain, placenta, and ovary. Furthermore, this antibody is useful for the purification of H-FABP. Aliases Fatty acid-binding protein 3, FABP3, Muscle fatty acid-binding protein, Mammary-derived growth inhibitor Immunogen Purified human H-FABP
- 途径
- Monocarboxylic Acid Catabolic Process
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