(4 references)-
- 抗原 See all CD36 抗体
- CD36
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适用
- 小鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CD36 antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Functional Studies (Func)
- 内毒素水平
- Low endotoxin level
- 克隆位点
- CRF D-2712
- Top Product
- Discover our top product CD36 Primary Antibody
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anti-CD36 (CD36) (Extracellular Domain) antibody
CD36 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-CD36 (CD36) (AA 99-114) antibodyCD36 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-CD36 (CD36) (C-Term) antibodyCD36 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-CD36 (CD36) (N-Term) antibodyCD36 适用: 人, 小鼠, 大鼠, Pig, 犬, 马, 兔, Cow, 山羊, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-CD36 (CD36) (AA 213-242) antibodyCD36 适用: 人 FACS, WB, IF, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-CD36 (CD36) (AA 51-150) antibodyCD36 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-CD36 (CD36) antibody (FITC)CD36 适用: 人 FACS 宿主: 小鼠 Monoclonal CB38 FITC
anti-CD36 (CD36) (AA 30-130) antibodyCD36 适用: 人 IHC, ELISA 宿主: 小鼠 Monoclonal 5B6F5 unconjugated
anti-CD36 (CD36) (AA 30-130) antibodyCD36 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 5B6B2 unconjugated
anti-CD36 (CD36) (N-Term) antibodyCD36 适用: 人, 大鼠, Pig, 犬, 马, 兔, Cow, 山羊 WB, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- For flow cytometry and Western blotting dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:25. For functional studies dilutions have to be made according to the amounts of CD36 binding to be blocked.
- 限制
- 仅限研究用
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- 缓冲液
- 2 mL(> 100 μg/mL) culture medium with low endotoxin level.
- 储存条件
- 4 °C
- 储存方法
- Product should be stored at 4 °C. Under recommended storage conditions, product is stable for one year.
- 有效期
- 12 months
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: "FoxO1 stimulates fatty acid uptake and oxidation in muscle cells through CD36-dependent and -independent mechanisms." in: The Journal of biological chemistry, Vol. 280, Issue 14, pp. 14222-9, (2005) (PubMed).
: "Scavenger receptors class A-I/II and CD36 are the principal receptors responsible for the uptake of modified low density lipoprotein leading to lipid loading in macrophages." in: The Journal of biological chemistry, Vol. 277, Issue 51, pp. 49982-8, (2002) (PubMed).
: "CD36-mediated nonopsonic phagocytosis of erythrocytes infected with stage I and IIA gametocytes of Plasmodium falciparum." in: Infection and immunity, Vol. 71, Issue 1, pp. 393-400, (2002) (PubMed).
: "Differential roles of CD36 and alphavbeta5 integrin in photoreceptor phagocytosis by the retinal pigment epithelium." in: The Journal of experimental medicine, Vol. 194, Issue 9, pp. 1289-98, (2001) (PubMed).
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: "FoxO1 stimulates fatty acid uptake and oxidation in muscle cells through CD36-dependent and -independent mechanisms." in: The Journal of biological chemistry, Vol. 280, Issue 14, pp. 14222-9, (2005) (PubMed).
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- 抗原
- CD36
- 别名
- CD36 (CD36 产品)
- 别名
- BDPLT10 antibody, CHDS7 antibody, FAT antibody, GP3B antibody, GP4 antibody, GPIV antibody, PASIV antibody, SCARB3 antibody, Fat antibody, Scarb3 antibody, GPIIIB antibody, PAS-4 antibody, zgc:92513 antibody, CD36 molecule antibody, CD36 molecule (thrombospondin receptor) antibody, CD36 antibody, Cd36 antibody, cd36 antibody
- 背景
- Monoclonal antibody CRF D-2712 (also known as JC63.1 or 63) reacts with mouse CD36 (85- kDa), a cell surface class B scavenger receptor. Recently, CD36 has been identified as a protein that is required for TLR2 recognition of di-acylated bacterial lipopeptides and lipoteichoic acid. CD36 is a heavily N- glycosylated transmembrane protein with two short intracellular domains and a large extracellular domain. CD36 expression is primarily controlled by the transcription heterodimer PPARg-RXR (peroxisome proliferator-activated receptor-g-retinoid-X-receptor). CD36 is preferentially found within lipid rafts, which facilitates its association with receptors, signalling and adaptor molecules. CD36 is expressed on monocytes, macrophages, endothelial cells, hepatocytes, erythrocytes, adipocytes, cardiomyocytes and red skeletal muscle. Importantly it is expressed by steriodogenic cells in the adrenal gland, testis and ovary. CD36 has been implicated in many biological processes including angiogenesis, phagocytosis, inflammation, and lipid and glucose metabolism. CD36 is associated with Src-family kinases and with the integrins alpha3beta1 and alpha6beta1. It is a receptor and transporter of oxidized lipids and long chain fatty acids. CD36 has been shown to function as phagocytic receptor for apoptotic cells. Several in vivo models support the role of the thrombospondin / CD36 system in angiogenesis and tumor growth. An important role for CD36 has been found in Malaria as major receptor for P. falciparum- infected red blood cells. Many different ligands have been reported to interact with CD36, suggesting that CD36 could recognize a structure-based domain rather than specific contact residues. Monoclonal antibody CRF D-2712 blocks CD36 binding. It is not known whether the antibody is activating or neutralizing. The antibody cross reacts with rat CD36.
- 途径
- TLR signaling, Peptide Hormone Metabolism, Response to Growth Hormone Stimulus, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Lipid Metabolism by PPARalpha, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Hepatitis C, Toll-Like Receptors Cascades, Lipid Metabolism, S100 Proteins
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