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IL-6 抗体

IL6 适用: 小鼠 IA, D, InhA 宿主: 大鼠 Monoclonal MP5-20F3 unconjugated
产品编号 ABIN2191746
发货至: 中国
  • 抗原 See all IL-6 (IL6) 抗体
    IL-6 (IL6) (Interleukin 6 (IL6))
    适用
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    小鼠
    宿主
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    大鼠
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    单克隆
    标记
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    This IL-6 antibody is un-conjugated
    应用范围
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    Immunoassay (IA), Detection (D), Inhibition Assay (InhA)
    过滤
    0.2 μm filtered
    克隆位点
    MP5-20F3
    Top Product
    Discover our top product IL6 Primary Antibody
  • 应用备注
    For neutralisation of biological activity dilutions have to be made according to the amount of IL-6 to be inactivated.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.1 % bovine serum albumin.
    储存条件
    4 °C
    储存方法
    Product should be stored at 4 °C. Under recommended storage conditions, product is stable for one year.
    有效期
    12 months
  • Hirano: "Interleukin 6 (IL-6) and its receptor: their role in plasma cell neoplasias." in: International journal of cell cloning, Vol. 9, Issue 3, pp. 166-84, (1991) (PubMed).

    Hooghe-Peters, Velkeniers, Vanhaelst, Hooghe: "Interleukin-1, interleukin-6: messengers in the neuroendocrine immune system?" in: Pathology, research and practice, Vol. 187, Issue 5, pp. 622-5, (1991) (PubMed).

    Takatsuki, Okano, Suzuki, Chieda, Takahara, Hirano, Kishimoto, Hamuro, Akiyama: "Human recombinant IL-6/B cell stimulatory factor 2 augments murine antigen-specific antibody responses in vitro and in vivo." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 141, Issue 9, pp. 3072-7, (1988) (PubMed).

    McKenzie: "Alloantigen presentation by B cells. Requirement for IL-1 and IL-6." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 141, Issue 9, pp. 2907-11, (1988) (PubMed).

  • 抗原
    IL-6 (IL6) (Interleukin 6 (IL6))
    别名
    Interleukin 6 (IL6 产品)
    别名
    BSF2 antibody, HGF antibody, HSF antibody, IFNB2 antibody, IL-6 antibody, Il-6 antibody, ILg6 antibody, Ifnb2 antibody, il6 antibody, CHIL-6 antibody, interleukin 6 antibody, interleukin-6 antibody, IL6 antibody, Il6 antibody, il-6 antibody, IL-6 antibody
    背景
    The antibody neutralizes mouse interleukin 6 (IL-6). It does not cross-react with LPS (the component of the bacterial cell wall which is considered responsible for the toxicity of gram-negative bacteria) and TNF- alpha nor does it bind to either human or rat IL-6. The antibody inhibits IL-6 induced proliferation of the B9 assay. IL-6 is a pluripotent 20-22 kDa cytokine which plays a role in the pathophysiology of severe infection and regulates the immune response, acute phase reaction and haematopoiesis. IL-6 plays a critical role in B-cell differentiation to plasma cells and is a potent growth factor for plasmacytoma and myeloma. Continuous IL-6 gene expression makes an essential contribution to a multistep oncogenesis of plasma cell neoplasia. IL-6 is a very useful culture supplement for the generation of a high number of antibody-producing hybridomas.
    途径
    TLR signaling, Hormone Transport, Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Autophagy, Cell RedoxHomeostasis, Cancer Immune Checkpoints, Inflammasome
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