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VEGFR2/CD309 抗体 (AA 101-200) (Cy5)

Name: VEGFR2/CD309 抗体 (AA 101-200) (Cy5)
SKU: ABIN2180051
Availability: OutOfStock

VEGFR2 适用: 人, 小鼠, 大鼠, 兔 FACS, IF (p) 宿主: 兔 Polyclonal Cy5

产品编号 ABIN2180051

发货至: 中国

Datasheet as PDF

抗原 See all VEGFR2/CD309 (VEGFR2) 抗体

VEGFR2/CD309 (VEGFR2) (VEGF Receptor 2 (VEGFR2))
抗原表位
42

36

27

25

20

16

15

15

15

10

10

8

8

6

6

6

5

5

4

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 101-200
适用
312

198

144

16

9

5

3

3

3

3

1

1

1

1

1

1

1

1

1

1
人, 小鼠, 大鼠, 兔
宿主
304

51

15

1

1

1
兔
Compatible Secondaries
克隆类型
297

76
多克隆
标记
163

34

20

13

13

12

7

7

7

7

7

7

6

6

6

6

6

6

6

6

6

6

5

2

2

1

1

1

1

1

1

1
This VEGFR2/CD309 antibody is conjugated to Cy5
应用范围
224

135

97

84

64

27

25

22

19

14

13

12

9

8

7

4

3

2

1
Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

交叉反应

人, 小鼠, 兔, 大鼠

预测反应

Dog,Cow,Sheep,Pig,Horse

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic peptide derived from human VEGFR2

亚型

IgG

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VEGFR2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-VEGF Receptor 2 (VEGFR2) (AA 20-242) antibody
VEGFR2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-VEGF Receptor 2 (VEGFR2) (AA 1326-1356) antibody
VEGFR2 适用: 人 WB, IHC, ELISA, FACS, IF 宿主: 兔 Polyclonal unconjugated

anti-VEGF Receptor 2 (VEGFR2) (AA 101-200) antibody
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anti-VEGF Receptor 2 (VEGFR2) (pTyr1214) antibody
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anti-VEGF Receptor 2 (VEGFR2) (AA 20-764) antibody
VEGFR2 适用: 人 WB, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 4B4 unconjugated

anti-VEGF Receptor 2 (VEGFR2) (AA 1225-1356) antibody
VEGFR2 适用: 人 WB, IHC, ELISA, FACS, ICC, Neut 宿主: 小鼠 Monoclonal 1A9A3 unconjugated

anti-VEGF Receptor 2 (VEGFR2) (AA 454-469), (Middle Region) antibody
VEGFR2 适用: 人 WB, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-VEGF Receptor 2 (VEGFR2) (AA 1326-1356), (C-Term) antibody
VEGFR2 适用: 人 WB, FACS, IF, IHC (p) 宿主: 兔 Polyclonal RB01536 unconjugated

应用备注

FCM 1:20-100
IF(IHC-P) 1:50-200

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

有效期

12 months
抗原

VEGFR2/CD309 (VEGFR2) (VEGF Receptor 2 (VEGFR2))

别名

VEGFR2 (VEGFR2 产品)

别名

CD309 antibody, FLK1 antibody, VEGFR antibody, VEGFR2 antibody, 6130401C07 antibody, Flk-1 antibody, Flk1 antibody, Krd-1 antibody, Ly73 antibody, VEGFR-2 antibody, sVEGFR-2 antibody, Vegfr-2 antibody, FLK-1 antibody, flk-1 antibody, vegfr-2 antibody, KDR antibody, FLK/KDR antibody, flk1 antibody, flk1b antibody, kdrb antibody, si:busm1-205d10.1 antibody, si:ch211-254j6.1 antibody, si:ch211-278f21.4 antibody, wu:fc31a09 antibody, fk52c05 antibody, flk antibody, kdr antibody, kdra antibody, vegfr2 antibody, vegfr4 antibody, vegr2 antibody, wu:fk52c05 antibody, kinase insert domain receptor antibody, kinase insert domain protein receptor antibody, vascular endothelial growth factor receptor kdr-like antibody, kinase insert domain receptor (a type III receptor tyrosine kinase) antibody, kinase insert domain receptor like antibody, KDR antibody, Kdr antibody, LOC100136647 antibody, kdr antibody, kdrl antibody

背景

Synonyms: FLK1, CD309, VEGFR, VEGFR2, Vascular endothelial growth factor receptor 2, VEGFR-2, Fetal liver kinase 1, FLK-1, Kinase insert domain receptor, KDR, Protein-tyrosine kinase receptor flk-1
Background: Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFC and VEGFD. Plays an essential role in the regulation of angiogenesis, vascular development, vascular permeability, and embryonic hematopoiesis. Promotes proliferation, survival, migration and differentiation of endothelial cells. Promotes reorganization of the actin cytoskeleton. Isoforms lacking a transmembrane domain, such as isoform 2 and isoform 3, may function as decoy receptors for VEGFA, VEGFC and/or VEGFD. Isoform 2 plays an important role as negative regulator of VEGFA- and VEGFC-mediated lymphangiogenesis by limiting the amount of free VEGFA and/or VEGFC and preventing their binding to FLT4. Modulates FLT1 and FLT4 signaling by forming heterodimers. Binding of vascular growth factors to isoform 1 leads to the activation of several signaling cascades. Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate and the activation of protein kinase C. Mediates activation of MAPK1/ERK2, MAPK3/ERK1 and the MAP kinase signaling pathway, as well as of the AKT1 signaling pathway. Mediates phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, reorganization of the actin cytoskeleton and activation of PTK2/FAK1. Required for VEGFA-mediated induction of NOS2 and NOS3, leading to the production of the signaling molecule nitric oxide (NO) by endothelial cells. Phosphorylates PLCG1. Promotes phosphorylation of FYN, NCK1, NOS3, PIK3R1, PTK2/FAK1 and SRC.

基因ID

3791

UniProt

P35968

途径

RTK signaling, Glycosaminoglycan Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling