INTU 抗体 (AbBy Fluor® 488)
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- 抗原 See all INTU 抗体
- INTU (Inturned Planar Cell Polarity Effector Homolog (INTU))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This INTU antibody is conjugated to AbBy Fluor® 488
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应用范围
- Western Blotting (WB)
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human PDZD6
- 亚型
- IgG
- Top Product
- Discover our top product INTU Primary Antibody
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- 应用备注
- IF(IHC-P) 1:50-200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- INTU (Inturned Planar Cell Polarity Effector Homolog (INTU))
- 别名
- PDZD6 (INTU 产品)
- 别名
- 9230116I04Rik antibody, 9430087H23Rik antibody, Pdzd6 antibody, Pdzk6 antibody, mKIAA1284 antibody, INT antibody, PDZD6 antibody, PDZK6 antibody, Xint antibody, in antibody, int antibody, pdzd6 antibody, inturned planar cell polarity protein antibody, inturned planar cell polarity protein S homeolog antibody, Intu antibody, INTU antibody, intu antibody, intu.S antibody
- 背景
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Synonyms: Protein inturned, Inturned planar cell polarity effector homolog, PDZ domain-containing protein 6, INTU, KIAA1284, PDZD6, PDZK6, INTU_HUMAN.
Background: Plays a key role in ciliogenesis and embryonic development. Regulator of cilia formation by controlling the organization of the apical actin cytoskeleton and the positioning of the basal bodies at the apical cell surface, which in turn is essential for the normal orientation of elongating ciliary microtubules. Plays a key role in definition of cell polarity via its role in ciliogenesis but not via conversion extension. Has an indirect effect on hedgehog signaling (By similarity). Proposed to function as core component of the CPLANE (ciliogenesis and planar polarity effectors) complex involved in the recruitment of peripheral IFT-A proteins to basal bodies (PubMed:27158779).
- 基因ID
- 27152
- UniProt
- Q9ULD6
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