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IL2RG 抗体 (AA 51-150)

Name: IL2RG 抗体 (AA 51-150)
SKU: ABIN2176981
Availability: OutOfStock

IL2RG 适用: 人, 大鼠 WB, FACS, ELISA 宿主: 兔 Polyclonal unconjugated

L1 rat spleen lysates L2 mouse heart lysates probed with Anti IL-2R gamma/CD132 Polyclonal Antibody, Unconjugated at 1:3000 for 90 min at 37˚C. (IL2RG 抗体 (AA 51-150))

Formalin-fixed and paraffin-embedded human lung labeled with Anti-IL-2R gamma Polyclonal Antibody, Unconjugatedused at 1:200 dilution for 40 minutes at 37°C. (IL2RG 抗体 (AA 51-150))

Formalin-fixed and paraffin embedded human lung tissue labeled with Rabbit Anti-IL-2R gamma Polyclonal Antibody at 1:200 followed by conjugation to the secondary antibody and DAB staining. (IL2RG 抗体 (AA 51-150))

IHC (p)

Human U937 cells probed with IL-2R gamma Polyclonal Antibody, Unconjugated (green) at 1:100 for 30 minutes followed by a PE conjugated secondary antibody compared to unstained cells (blue), secondary only (light blue), and isotype control (orange). (IL2RG 抗体 (AA 51-150))

FACS

IHC (p)

5 images

产品编号 ABIN2176981

发货至: 中国

Datasheet as PDF

抗原 See all IL2RG 抗体

IL2RG (Interleukin 2 Receptor, gamma (IL2RG))
抗原表位
15

7

5

5

3

3

3

2

2

2

2

2

1

1

1

1

1

1
AA 51-150
适用
66

26

24

3

1
人, 大鼠
宿主
54

11

9
兔
Compatible Secondaries
克隆类型
57

17
多克隆
标记
33

9

4

4

4

3

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This IL2RG antibody is un-conjugated
应用范围
48

30

22

7

3

2

2

2

1

1

1

1
Western Blotting (WB), Flow Cytometry (FACS), ELISA

交叉反应

人, 大鼠

预测反应

Mouse,Dog,Cow,Pig

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic peptide derived from human IL-2R gamma

亚型

IgG
anti-Interleukin 2 Receptor, gamma (IL2RG) (AA 23-262) antibody
IL2RG 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4A8F2 unconjugated

anti-Interleukin 2 Receptor, gamma (IL2RG) (AA 76-101), (N-Term) antibody
IL2RG 适用: 人 WB, FACS, IF 宿主: 兔 Polyclonal RB22117 unconjugated

anti-Interleukin 2 Receptor, gamma (IL2RG) (AA 23-262) antibody
IL2RG 适用: 人 WB, ELISA, ICC, IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Interleukin 2 Receptor, gamma (IL2RG) (AA 23-263) antibody
IL2RG 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Interleukin 2 Receptor, gamma (IL2RG) antibody (APC)
IL2RG 适用: 人, 犬 FACS 宿主: 大鼠 Monoclonal TUGh4 APC

anti-Interleukin 2 Receptor, gamma (IL2RG) (AA 75-230) antibody
IL2RG 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Interleukin 2 Receptor, gamma (IL2RG) (N-Term) antibody
IL2RG 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Interleukin 2 Receptor, gamma (IL2RG) antibody
IL2RG 适用: 人, 犬 FACS 宿主: 大鼠 Monoclonal TUGh4 unconjugated

anti-Interleukin 2 Receptor, gamma (IL2RG) (AA 23-260) antibody
IL2RG 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-Interleukin 2 Receptor, gamma (IL2RG) (AA 1-369) antibody
IL2RG 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

应用备注

WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

有效期

12 months
抗原

IL2RG (Interleukin 2 Receptor, gamma (IL2RG))

别名

IL-2R gamma (IL2RG 产品)

别名

Ab2-183 antibody, Cd132 antibody, CD132 antibody, CIDX antibody, IL-2RG antibody, IMD4 antibody, P64 antibody, SCIDX antibody, SCIDX1 antibody, [g]c antibody, gamma(c) antibody, gc antibody, interleukin 2 receptor subunit gamma antibody, interleukin 2 receptor subunit gamma L homeolog antibody, interleukin 2 receptor, gamma chain antibody, IL2RG antibody, il2rg.L antibody, Il2rg antibody

背景

Synonyms: P64, CIDX, IMD4, CD132, SCIDX, IL-2RG, SCIDX1, Cytokine receptor common subunit gamma, Interleukin-2 receptor subunit gamma, IL-2 receptor subunit gamma, IL-2R subunit gamma, gammaC, IL2RG
Background: Interleukin 2 (IL2) receptor gamma chain (IL5212R gamma) is a cell surface glycoprotein expressed by a variety of leukocytes including T cells, B cells, NK cells, monocytes, macrophages, and neutrophils. IL2R gamma is also known as CD132, common cytokine receptor gamma chain, and gamma c. IL2R gamma forms complexes with other cell surface proteins including CD25 (IL2R alpha), CD122 (IL2R beta), CD124 (IL4R alpha), CD127 (IL7R), and others. IL2R gamma complexed with other cell surface proteins forms receptors for the cytokines IL2, IL4, IL7, IL9, and IL15. Acting through the IL2R gamma containing complexes, these cytokines regulate lymphocyte development and activation. Chemical cross linking experiments reveal that IL2R gamma is able to bind cytokines only when complexed with these other cell surface proteins. In addition to interacting with other cell surface glycoproteins, IL2R gamma associates with several cytoplasmic tyrosine kinases including JAK3 (Janus Kinase 3), JAK1, Syc, and Lyc. Cytokine binding to the IL2R gamma containing receptor complexes activates these tyrosine kinases. Once activated, these tyrosine kinases phosphorylate their associated receptors, creating docking sites for signaling molecules such as PI 3 kinase. The activated tyrosine kinases also phosphorylate downstream regulators including STAT3 (Signal Transducer and Activator of Transcription 3), STAT5, and STAT6. The various cytokines that bind to IL2R gamma containing receptor complexes exert their effects through unique repertoires of cytoplasmic signaling molecules. IL2, IL7, and IL9 exert their effects through cascades, which activate STAT3 and STAT5, while IL4 activates STAT6. IL2 and IL15 exert their effects through cascades, which activate the MAP kinase cascade. IL7 exerts its effects through a cascade that results in VDJ immunoglobulin gene rearrangement.

基因ID

3561

UniProt

P31785

途径

JAK/STAT Signaling, Growth Factor Binding