SIP1 抗体 (AA 51-150)
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- 抗原 See all SIP1 (GEMIN2) 抗体
- SIP1 (GEMIN2) (Gem (Nuclear Organelle) Associated Protein 2 (GEMIN2))
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抗原表位
- AA 51-150
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适用
- 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SIP1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc))
- 交叉反应
- 大鼠
- 预测反应
- Human,Mouse,Cow,Horse,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human SIP1/Gemin 2
- 亚型
- IgG
- Top Product
- Discover our top product GEMIN2 Primary Antibody
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- SIP1 (GEMIN2) (Gem (Nuclear Organelle) Associated Protein 2 (GEMIN2))
- 别名
- Gemin 2 (GEMIN2 产品)
- 别名
- SIP1 antibody, SIP1-delta antibody, 1700012N19Rik antibody, Sip1 antibody, sip1 antibody, sip1-delta antibody, wu:fc52a05 antibody, zgc:110274 antibody, gem nuclear organelle associated protein 2 antibody, gem (nuclear organelle) associated protein 2 antibody, gem nuclear organelle associated protein 2 S homeolog antibody, GEMIN2 antibody, Gemin2 antibody, gemin2.S antibody, gemin2 antibody
- 背景
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Synonyms: SIP1, SIP1-delta, Gem-associated protein 2, Gemin-2, Component of gems 2, Survival of motor neuron protein-interacting protein 1, SMN-interacting protein 1, GEMIN2
Background: The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP. Dissociation by the SMN complex of CLNS1A from the trapped Sm proteins and their transfer to an SMN-Sm complex triggers the assembly of core snRNPs and their transport to the nucleus.
- 基因ID
- 8487
- UniProt
- O14893
- 途径
- Ribonucleoprotein Complex Subunit Organization, Tube Formation
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