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FAM48A/P38IP 抗体 (AA 21-120) (Cy3)

SUPT20H 适用: 人 IF (cc), IF (p) 宿主: 兔 Polyclonal Cy3
产品编号 ABIN2174052
发货至: 中国
  • 抗原 See all FAM48A/P38IP (SUPT20H) 抗体
    FAM48A/P38IP (SUPT20H) (Suppressor of Ty 20 Homolog (SUPT20H))
    抗原表位
    • 14
    • 2
    • 1
    • 1
    AA 21-120
    适用
    • 19
    • 3
    • 2
    宿主
    • 19
    克隆类型
    • 19
    多克隆
    标记
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FAM48A/P38IP antibody is conjugated to Cy3
    应用范围
    • 12
    • 12
    • 5
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    预测反应
    Human,Mouse,Rat,Cow
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human FAM48A
    亚型
    IgG
    Top Product
    Discover our top product SUPT20H Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    FAM48A/P38IP (SUPT20H) (Suppressor of Ty 20 Homolog (SUPT20H))
    别名
    Fam48a (SUPT20H 产品)
    别名
    SUPT20H antibody, AA667204 antibody, AI450544 antibody, D3Ertd300e antibody, Fam48a antibody, Supt20h antibody, p38IP antibody, RGD1307812 antibody, C13 antibody, C13orf19 antibody, FAM48A antibody, P38IP antibody, SPT20 antibody, bA421P11.4 antibody, SPT20 homolog, SAGA complex component antibody, suppressor of Ty 20 antibody, SUPT20H antibody, Supt20 antibody, Supt20h antibody
    背景

    Synonyms: FAM48A is a 779 amino acid protein that interacts with p38 MAP kinase. Specifically, FAM48A and p38 are required for downregulation of E-cadherin during gastrulation. In adult tissues, FAM48A is highly expressed in testis and moderately expressed in brain and pituitary gland. It is also expressed in several fetal tissues, including lung, brain, thymus and kidney. Expression of FAM48A has been shown to be downregulated in malignant prostate tissues. The gene encoding FAM48A maps to human chromosome 13, which houses over 400 genes and comprises approximately 4 % of the human genome. Key tumor suppressor genes on chromosome 13 include the breast cancer susceptibility gene, BRCA2, and the RB1 (retinoblastoma) gene.

    Background: FAM48A is a 779 amino acid protein that interacts with p38 MAP kinase. Specifically, FAM48A and p38 are required for downregulation of E-cadherin during gastrulation. In adult tissues, FAM48A is highly expressed in testis and moderately expressed in brain and pituitary gland. It is also expressed in several fetal tissues, including lung, brain, thymus and kidney. Expression of FAM48A has been shown to be downregulated in malignant prostate tissues. The gene encoding FAM48A maps to human chromosome 13, which houses over 400 genes and comprises approximately 4 % of the human genome. Key tumor suppressor genes on chromosome 13 include the breast cancer susceptibility gene, BRCA2, and the RB1 (retinoblastoma) gene.

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