Claudin 22 (CLDN22) (AA 101-180) 抗体 (Cy5)
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- 抗原 See all Claudin 22 (CLDN22) 抗体
- Claudin 22 (CLDN22)
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抗原表位
- AA 101-180
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- Cy5
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应用范围
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 预测反应
- Human
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human Claudin 22
- 亚型
- IgG
- Top Product
- Discover our top product CLDN22 Primary Antibody
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- Claudin 22 (CLDN22)
- 别名
- Claudin 22 (CLDN22 产品)
- 别名
- CLDN21 antibody, 2210404A22Rik antibody, 5330431C14Rik antibody, 9530051B05Rik antibody, CLDN22 antibody, claudin 22 antibody, claudin-22 antibody, CLDN22 antibody, Cldn22 antibody, LOC102186369 antibody
- 背景
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Synonyms: Claudin-22, CLD22_HUMAN, CLDN21,CLDN22, FLJ51450.
Background: The claudin superfamily consists of many structurally related proteins that are important structural and functional components of tight junctions in paracellular transport. Claudins are located in both epithelial and endothelial cells in all tight junction-bearing tissues. Claudins, which consist of four transmembrane domains and two extracellular loops, make up tight junction strands. It is suggested that the claudin family of proteins regulate transport through tight junctions via differential discrimination for solute size and charge. Claudin expression is often highly restricted to specific regions of different tissues and may have an important role in transcellular transport through tight junctions. Claudin-22, also known as CLDN22, is a 220 amino acid member of the claudin family that participates in tight junction-specific obliteration of the intercellular space through calcium-independent cell-adhesion activity.
- 途径
- Cell-Cell Junction Organization, Hepatitis C
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