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FAT4 抗体 (AA 4351-4450) (Biotin)

FAT4 适用: 小鼠, 大鼠 ELISA, WB, IHC (fro), IHC (p) 宿主: 兔 Polyclonal Biotin
产品编号 ABIN2172808
发货至: 中国
  • 抗原 See all FAT4 抗体
    FAT4 (FAT Tumor Suppressor Homolog 4 (FAT4))
    抗原表位
    • 14
    • 5
    • 2
    • 1
    AA 4351-4450
    适用
    • 18
    • 14
    • 14
    小鼠, 大鼠
    宿主
    • 29
    • 3
    克隆类型
    • 29
    • 3
    多克隆
    标记
    • 9
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FAT4 antibody is conjugated to Biotin
    应用范围
    • 20
    • 13
    • 13
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    小鼠, 大鼠
    预测反应
    Human,Dog,Cow,Sheep,Pig,Horse
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human CDHF14
    亚型
    IgG
    Top Product
    Discover our top product FAT4 Primary Antibody
  • 应用备注
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C for 12 months.
    有效期
    12 months
  • 抗原
    FAT4 (FAT Tumor Suppressor Homolog 4 (FAT4))
    别名
    CDHF14 (FAT4 产品)
    别名
    CDHF14 antibody, CDHR11 antibody, FAT-J antibody, FATJ antibody, NBLA00548 antibody, 6030410K14Rik antibody, 9430004M15 antibody, FAT atypical cadherin 4 antibody, FAT4 antibody, Fat4 antibody
    背景

    Synonyms: Cadherin family member 14, CDHF14, FAT tumor suppressor homolog 4, Fat-like cadherin protein FAT-J, FAT4, FAT4_HUMAN, FATJ, hFat4, Nbla00548, Protocadherin Fat 4.

    Background: The cadherins represent a family of Ca2+-dependent adhesion molecules that function to mediate cell to cell binding that is critical for the maintenance of structure and morphogenesis. Cadherins contain a large extracellular domain at the N-terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short C-terminal intracellular domain interacts with a variety of cytoplasmic proteins, including beta-catenin, to regulate cadherin function. The cadherin superfamily includes cadherins, protocadherins, desmogleins and desmocollins. FAT4 (FAT tumor suppressor homolog 4), also known as FAT-J, CDHF14 or CDHR11, is a 4,981 amino acid single-pass type I membrane protein that belongs to the protocadherin subfamily of cadherins and localizes to the primary cilia of kidney. Widely expressed, FAT4 contains thirty-four cadherin domains, six EGF-like domains and two laminin G-like domains. FAT4 may function in the regulation of planar cell polarity.

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