ADAM33 抗体 (AA 701-800) (Biotin)
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- 抗原 See all ADAM33 抗体
- ADAM33 (ADAM Metallopeptidase Domain 33 (ADAM33))
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抗原表位
- AA 701-800
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适用
- 非洲爪蟾
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ADAM33 antibody is conjugated to Biotin
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 非洲爪蟾
- 交叉反应 （详细）
- Xenopus laevis
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from Xenopus laevis ADAM13
- 亚型
- IgG
- Top Product
- Discover our top product ADAM33 Primary Antibody
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anti-ADAM Metallopeptidase Domain 33 (ADAM33) (AA 140-420) antibody
ADAM33 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-ADAM Metallopeptidase Domain 33 (ADAM33) (AA 140-420) antibodyADAM33 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-ADAM Metallopeptidase Domain 33 (ADAM33) (Internal Region) antibodyADAM33 适用: 人 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-ADAM Metallopeptidase Domain 33 (ADAM33) (C-Term) antibodyADAM33 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-ADAM Metallopeptidase Domain 33 (ADAM33) (AA 210-503) antibodyADAM33 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-ADAM Metallopeptidase Domain 33 (ADAM33) (AA 551-650) antibodyADAM33 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-ADAM Metallopeptidase Domain 33 (ADAM33) (Internal Region) antibodyVerified ADAM33 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-ADAM Metallopeptidase Domain 33 (ADAM33) (AA 295-344) antibodyADAM33 适用: 人, 小鼠, 大鼠, 犬, 马, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-ADAM Metallopeptidase Domain 33 (ADAM33) (AA 587-650) antibodyADAM33 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-ADAM Metallopeptidase Domain 33 (ADAM33) (AA 500-700) antibodyADAM33 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- ADAM33 (ADAM Metallopeptidase Domain 33 (ADAM33))
- 别名
- ADAM13 (ADAM33 产品)
- 别名
- ADAM13 antibody, ADAM33 antibody, Adaml antibody, adam13 antibody, C20orf153 antibody, DJ964F7.1 antibody, ADAM metallopeptidase domain 33 antibody, disintegrin and metalloproteinase domain-containing protein 19-like antibody, a disintegrin and metallopeptidase domain 33 antibody, ADAM metallopeptidase domain 33 L homeolog antibody, ADAM33 antibody, LOC100230755 antibody, Adam33 antibody, adam33.L antibody
- 背景
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Synonyms: NULL
Background: ADAM13 was first described as a protein expressed in somatic mesoderm and neural crest cells, in developing Xenopus embryos. ADAM13 was also found in liver, heart, and intestines from adult Xenopus. ADAM13 may regulate cellular signaling via Src and Src tyrosine kinase. ADAM13 may also act as a cell attachment molecule, by binding integrins through the cysteine rich domain amoung many other roles. A member of the metalloproteinase family containing disintegrin like domains (ADAMs) the functions of ADAM13 are still poorly understood. ADAM13 contains the canonical HExxHxxxxxH zinc metalloproteinase motif, as well as disintegrin, cysteine rich, EFG like, transmembrane and Cytoplasmic domains. ADAM13 has been shown to be proteolytically active, cleaving fibronectin after binding it to the EGF like domain. ADAM13 is also shed from cells in culture, cleaved aminoterminal from the transmembrane domain, and is released into the culture media. Shed ADAM13 is a 52 kD protein, and can form complexes with a2 macroglobulin, suggesting it is a competent protease. Xenopus ADAM13 has greatest homology with human ADAM 33 (51 % identical), and is 46 % identical with human or mouse ADAM12 or ADAM19. It is still unclear if any of these ADAMs are species orthologs of Xenopus ADAM13, but there are significant differences between the related sequences, suggesting that ADAM13 may be a unique protein. The full length Xenopus ADAM13 sequence codes for a 914 amino acid protein. Predicted mass is 99.749 kD, but glycosylation and cyteine rich regions give Xenopus ADAM13 an apparent MW of 120 kD unprocessed, and 97 kD processed forms, on reduced SDS PAGE gels. ADAM13 contains a putative furin cleavage site, suggesting that a prohormone convertase cleaves the propeptide domain away from the catalytic domain
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