ALOX15 抗体 (AA 581-662)
(1 reference)-
- 抗原 See all ALOX15 抗体
- ALOX15 (Arachidonate 15-Lipoxygenase (ALOX15))
-
抗原表位
- AA 581-662
-
适用
- 人, 大鼠, 小鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This ALOX15 antibody is un-conjugated
-
应用范围
- ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 人, 小鼠, 大鼠
- 预测反应
- Cow,Pig
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human ALOX15/15 Lipoxygenase 1
- 亚型
- IgG
- Top Product
- Discover our top product ALOX15 Primary Antibody
-
anti-Arachidonate 15-Lipoxygenase (ALOX15) antibody
ALOX15 适用: 人, 大鼠, 猴, 犬 WB, IHC, IHC (p), IF 宿主: 小鼠 Monoclonal 3G8 unconjugated
anti-Arachidonate 15-Lipoxygenase (ALOX15) (AA 1-662) antibodyALOX15 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3D8 unconjugated
anti-Arachidonate 15-Lipoxygenase (ALOX15) (AA 2-337) antibodyALOX15 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Arachidonate 15-Lipoxygenase (ALOX15) (AA 170-312) antibodyALOX15 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C2 unconjugated
anti-Arachidonate 15-Lipoxygenase (ALOX15) (AA 1-662) antibodyALOX15 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Arachidonate 15-Lipoxygenase (ALOX15) (Internal Region) antibodyVerified ALOX15 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Arachidonate 15-Lipoxygenase (ALOX15) (AA 610-643), (C-Term) antibodyALOX15 适用: 人 WB, IHC (p), IF 宿主: 兔 Polyclonal RB17156 unconjugated
anti-Arachidonate 15-Lipoxygenase (ALOX15) (AA 1-225) antibodyALOX15 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Arachidonate 15-Lipoxygenase (ALOX15) (AA 1-663) antibodyALOX15 适用: 人 WB, IHC, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3D8 unconjugated
anti-Arachidonate 15-Lipoxygenase (ALOX15) antibodyALOX15 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
-
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
-
-
: "IL-4 drives microglia and macrophages toward a phenotype conducive for tissue repair and functional recovery after spinal cord injury." in: Glia, Vol. 64, Issue 12, pp. 2079-2092, (2016) (PubMed).
-
: "IL-4 drives microglia and macrophages toward a phenotype conducive for tissue repair and functional recovery after spinal cord injury." in: Glia, Vol. 64, Issue 12, pp. 2079-2092, (2016) (PubMed).
-
- 抗原
- ALOX15 (Arachidonate 15-Lipoxygenase (ALOX15))
- 别名
- 15 Lipoxygenase 1 (ALOX15 产品)
- 别名
- 15-LOX-1 antibody, 15LOX-1 antibody, ALOX15 antibody, 12-LO antibody, Alox12l antibody, L-12LO antibody, 12-LOX antibody, Alox12 antibody, ALOX12 antibody, 15-LOX antibody, Alox12e antibody, arachidonate 15-lipoxygenase antibody, Arachidonate 15-lipoxygenase antibody, ALOX15 antibody, Alox15 antibody, Nmul_A0532 antibody, Sden_1680 antibody, Swoo_2919 antibody, PCC8801_3106 antibody, Cyan8802_3014 antibody, Nwat_1315 antibody
- 背景
-
Synonyms: 12-LOX, 15LOX-1, 15-LOX-1, Arachidonate 15-lipoxygenase, 15-LOX, 12/15-lipoxygenase, Arachidonate 12-lipoxygenase, leukocyte-type, Arachidonate omega-6 lipoxygenase, ALOX15, LOG15
Background: Non-heme iron-containing dioxygenase that catalyzes the stereo-specific peroxidation of free and esterified polyunsaturated fatty acids generating a spectrum of bioactive lipid mediators. Converts arachidonic acid into 12-hydroperoxyeicosatetraenoic acid/12-HPETE and 15-hydroperoxyeicosatetraenoic acid/15-HPETE. Also converts linoleic acid to 13-hydroperoxyoctadecadienoic acid. May also act on (12S)-hydroperoxyeicosatetraenoic acid/(12S)-HPETE to produce hepoxilin A3. Probably plays an important role in the immune and inflammatory responses. Through the oxygenation of membrane-bound phosphatidylethanolamine in macrophages may favor clearance of apoptotic cells during inflammation by resident macrophages and prevent an autoimmune response associated with the clearance of apoptotic cells by inflammatory monocytes. In parallel, may regulate actin polymerization which is crucial for several biological processes, including macrophage function. May also regulate macrophage function through regulation of the peroxisome proliferator activated receptor signaling pathway. Finally, it is also involved in the cellular response to IL13/interleukin-13. In addition to its role in the immune and inflammatory responses, may play a role in epithelial wound healing in the cornea maybe through production of lipoxin A4. May also play a role in endoplasmic reticulum stress response and the regulation of bone mass.
- 基因ID
- 246
- UniProt
- P16050
- 途径
- Regulation of Actin Filament Polymerization
-
