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Retinoblastoma Protein (Rb) 抗体 (Cleavage Site)

Name: Retinoblastoma Protein (Rb) 抗体 (Cleavage Site)
SKU: ABIN207915
Availability: OutOfStock

Rb Protein 适用: 人, 小鼠 WB, IHC 宿主: 小鼠 Monoclonal 172C1094 unconjugated

Image no. 2 for anti-Retinoblastoma Protein (Rb Protein) (Cleavage Site) antibody (ABIN207915) (Retinoblastoma Protein (Rb) 抗体 (Cleavage Site))

Image no. 1 for anti-Retinoblastoma Protein (Rb Protein) (Cleavage Site) antibody (ABIN207915) (Retinoblastoma Protein (Rb) 抗体 (Cleavage Site))

2 images

产品编号 ABIN207915

发货至: 中国

Datasheet as PDF

抗原 See all Retinoblastoma Protein (Rb) (Rb Protein) 抗体

Retinoblastoma Protein (Rb) (Rb Protein) (Retinoblastoma Protein (Rb Protein))
抗原表位
16

15

14

14

14

10

9

9

8

7

7

4

4

3

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Cleavage Site
适用
179

74

60

8

8

7

7

5

3

3

3

2

1

1

1
人, 小鼠
宿主
156

24
小鼠
Compatible Secondaries
克隆类型
154

26
单克隆
标记
90

17

10

9

9

9

6

6

6

6

6

6
This Retinoblastoma Protein (Rb) antibody is un-conjugated
应用范围
93

92

85

28

26

17

13

9

2
Western Blotting (WB), Immunohistochemistry (IHC)

特异性

Recognizes cleaved Rb (DRb-p70). Does not recognize full-length Rb. In camptothecin treated HL60, an ~68 kD band is observed. DRb-p70 exists in vivo as an N-terminally truncated form of Rb (Liu et al.). DRb-p70 is thought to be the product of alternative translation and is expressed in primary myeloid cells in fetal liver, bone marrow and spleen. DRb-p70 is also specifically expressed in tumor-associated macrophages (TAMs). TAMs are an important targets of cancer therapy. DRb-p70 is a marker of TAMs, and maybe useful for identifying tumors with macrophage infiltration (Liu et al, 2005).

纯化方法

Protein G purified

免疫原

A synthetic peptide corresponding to a region of the caspase-3-induced cleavage site of human Rb.

Type of Immunogen: Synthetic peptide

克隆位点

172C1094

亚型

IgG1

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Rb Protein 适用: 人, 小鼠, 大鼠, Cow, 犬, 猴, Pig, 马, Bat WB 宿主: 兔 Polyclonal unconjugated

anti-Retinoblastoma Protein (Rb Protein) (N-Term) antibody
Rb Protein 适用: 人, 小鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated

anti-Retinoblastoma Protein (Rb Protein) (C-Term) antibody
Rb Protein 适用: 人, Cow, 犬, Pig, Bat, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated

应用备注

Approved: IHC, WB (2 μg/mL)

Not recommended for: IHC-P

说明

Target Species of Antibody: Human

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

PBS, 0.02 % sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-80 °C

储存方法

Short term: 4°C
Long term: -70°C.
抗原

Retinoblastoma Protein (Rb) (Rb Protein) (Retinoblastoma Protein (Rb Protein))

别名

RB1 / Retinoblastoma / RB (Rb Protein 产品)

背景

Name/Gene ID: RB1

Synonyms: RB1, p105-Rb, Osteosarcoma, PRb, Retinoblastoma, Retinoblastoma 1, OSRC, RB, Pp110

基因ID

5925

UniProt

P06400

途径

Mitotic G1-G1/S Phases