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GLRA1 抗体 (N-Term)

GLRA1 适用: 人 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2017608
发货至: 中国
  • 抗原 See all GLRA1 抗体
    GLRA1 (Glycine Receptor, alpha 1 (GLRA1))
    抗原表位
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 30
    • 16
    • 16
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 27
    • 4
    • 1
    克隆类型
    • 27
    • 4
    多克隆
    标记
    • 21
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    This GLRA1 antibody is un-conjugated
    应用范围
    请咨询
    特异性
    Alpha 1 Glycine Receptor Antibody, pAb, Rabbit detects endogenous levels of mouse alpha 1 Glycine Receptor.
    交叉反应
    小鼠
    交叉反应 (详细)
    It is predicted to react with human alpha 1 Glycine Receptor according to sequence homology.
    Reactivity to other species is not tested yet.
    产品特性
    alpha 1 Glycine Receptor Antibody, pAb, Rabbit is developed in rabbit using a KLH-coupled synthetic peptide from N-terminal of human alpha 1 Glycine Receptor (Swiss Prot: P23415).
    纯化方法
    Immunoaffinity chromatography
    免疫原
    KLH-coupled synthetic peptide from N-terminal of human alpha 1 Glycine Receptor
    亚型
    IgG
    Top Product
    Discover our top product GLRA1 Primary Antibody
  • 说明

    Positive Control: Mouse brain

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstitute the lyophilized powder with deionized water (or equivalent) to an antibody concentration of 0.5 mg/mL.
    浓度
    0.5 mg/mL
    缓冲液
    Lyophilized with PBS, pH 7.4, containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    The antibody is stable in lyophilized form if stored at -20°C or below. The reconstituted antibody can be stored for 2-3 weeks at 2-8°C. For long term storage, aliquot and store at -20°C or below.
  • 抗原
    GLRA1 (Glycine Receptor, alpha 1 (GLRA1))
    Abstract
    GLRA1 产品
    别名
    GLYRA1 antibody, HKPX1 antibody, STHE antibody, [a]Z1 antibody, B230397M16Rik antibody, nmf11 antibody, oscillator antibody, ot antibody, spasmodic antibody, spd antibody, glycine receptor alpha 1 antibody, glycine receptor, alpha 1 antibody, glycine receptor, alpha 1 subunit antibody, GLRA1 antibody, Glra1 antibody, glra1 antibody
    背景
    The glycine receptor is a neurotransmitter-gated ion channel. Glycine is an important inhibitory transmitter in the brainstem and spinal cord. Binding of glycine to its receptor increases the chloride conductance and thus produces hyperpolarization. The alpha-1 subunit of the glycine receptor is a ligand-gated chloride channel. This inhibitory glycine receptor mediates postsynaptic inhibition in the spinal cord and other regions of the central nervous system. It is a pentameric receptor composed of alpha and beta subunits. Defects in alpha 1 Glycine Receptor are implicated in the pathophysiology of startle disease (STHE).
    分子量
    Predicted Band Size: 52 KD
    Observed Band Size: 48 KD
    UniProt
    P23415
    途径
    Synaptic Membrane
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