BRCA2 抗体 (AA 2480-2530)
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- 抗原 See all BRCA2 抗体
- BRCA2 (Breast Cancer 2, Early Onset (BRCA2))
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抗原表位
- AA 2480-2530
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This BRCA2 antibody is un-conjugated
- 应用范围
- 请咨询
- 特异性
- BRCA2 Antibody detects endogenous levels of human and mouse BRCA2.
- 交叉反应
- 小鼠
- 产品特性
- BRCA2 Antibody is developed in rabbit using a KLH-coupled synthetic peptide within residues 2480-2530 of human BRCA2 (Swiss Prot: P51587).
- 纯化方法
- Immunoaffinity chromatography.
- 免疫原
- KLH-coupled synthetic peptide within residues 2480-2530 of human BRCA2
- 亚型
- IgG
- Top Product
- Discover our top product BRCA2 Primary Antibody
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- 说明
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Positive Control: HEK293 and Mouse brain
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Reconstitute the lyophilized powder with deionized water (or equivalent) to an antibody concentration of 0.5 mg/mL.
- 浓度
- 0.5 mg/mL
- 缓冲液
- Lyophilized with PBS, pH 7.4, containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing cycles.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- The antibody is stable in lyophilized form if stored at -20°C or below. The reconstituted antibody can be stored for 2-3 weeks at 2-8°C. For long term storage, aliquot and store at -20°C or below.
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- 抗原
- BRCA2 (Breast Cancer 2, Early Onset (BRCA2))
- 别名
- BRCA2 (BRCA2 产品)
- 别名
- BRCC2 antibody, BROVCA2 antibody, FACD antibody, FAD antibody, FAD1 antibody, FANCB antibody, FANCD antibody, FANCD1 antibody, GLM3 antibody, PNCA2 antibody, 30169 antibody, BcDNA:SD25109 antibody, CG13583 antibody, CG13584 antibody, CG30169 antibody, Dmel\\CG30169 antibody, brca2 antibody, dmbrca2 antibody, fancd1 antibody, BRCA2 antibody, brcc2 antibody, brovca2 antibody, facd antibody, fad antibody, fad1 antibody, fancb antibody, AI256696 antibody, AW045498 antibody, Fancd1 antibody, RAB163 antibody, BRCA2, DNA repair associated antibody, Breast cancer 2, early onset homolog antibody, breast cancer 2, early onset antibody, BRCA2 antibody, Brca2 antibody, brca2 antibody, LOC584780 antibody
- 背景
- Breast cancer type 2 susceptibility protein (BRCA2) is involved in double-strand break repair and/or homologous recombination. It may participate in S phase checkpoint activation. In addition, It interacts with RAD51 and DSS1 and binds to ubiquitinated FANCD2. It also interacts with PALB2, enabling the recombinational repair and checkpoints functions. Defects in BRCA2 can cause genetic susceptibility to breast cancer (BC), also called susceptibility to familial breast-ovarian cancer type 2 (BROVCA2).
- 分子量
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Predicted Band Size: 390 KD
Observed Band Size: 390 KD - UniProt
- P51587
- 途径
- DNA Damage Repair, M Phase, Maintenance of Protein Location
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