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CNTNAP2 抗体 (C-Term)

CNTNAP2 适用: 人 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2017587
发货至: 中国
  • 抗原 See all CNTNAP2 抗体
    CNTNAP2 (Contactin Associated Protein-Like 2 (CNTNAP2))
    抗原表位
    • 16
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    C-Term
    适用
    • 44
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    宿主
    • 41
    • 4
    克隆类型
    • 43
    • 2
    多克隆
    标记
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    This CNTNAP2 antibody is un-conjugated
    应用范围
    请咨询
    特异性
    Rabbit Anti-Caspr2 Polyclonal Antibody detects endogenous levels of mouse and rat Caspr2.
    交叉反应
    小鼠, 大鼠
    交叉反应 (详细)
    It is predicted to react with human Caspr2 according to sequence homology.
    This product has not been tested for other species yet.
    产品特性
    Rabbit Anti-Caspr2 Polyclonal Antibody is developed in rabbit using a KLH-coupled synthetic peptide from C-terminal of human Caspr2 (Swiss Prot: Q9UHC6).
    纯化方法
    Immunoaffinity chromatography
    免疫原
    KLH-coupled synthetic peptide from C-terminal of human Caspr2.
    亚型
    IgG
    Top Product
    Discover our top product CNTNAP2 Primary Antibody
  • 说明

    Positive Control: mouse brain and rat brain.

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstitute the lyophilized powder with deionized water (or equivalent) to an antibody concentration of 0.5 mg/mL.
    浓度
    0.5 mg/mL
    缓冲液
    Lyophilized with PBS, pH 7.4, containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    The antibody is stable in lyophilized form if stored at -20°C or below. The reconstituted antibody can be stored for 2-3 weeks at 2-8°C. For long term storage, aliquot and store at -20°C or below.
  • Chen, Koopmans, Gordon, Paliukhovich, Klaassen, van der Schors, Peles, Verhage, Smit, Li: "Interaction proteomics of canonical Caspr2 (CNTNAP2) reveals the presence of two Caspr2 isoforms with overlapping interactomes." in: Biochimica et biophysica acta, Vol. 1854, Issue 7, pp. 827-33, (2015) (PubMed).

  • 抗原
    CNTNAP2 (Contactin Associated Protein-Like 2 (CNTNAP2))
    别名
    Caspr2 (CNTNAP2 产品)
    别名
    AUTS15 antibody, CASPR2 antibody, CDFE antibody, NRXN4 antibody, PTHSL1 antibody, 5430425M22Rik antibody, Caspr2 antibody, mKIAA0868 antibody, CASPR antibody, MGC145769 antibody, MGC147944 antibody, MGC147981 antibody, contactin associated protein like 2 antibody, contactin associated protein-like 2 antibody, contactin associated protein like 2b antibody, CNTNAP2 antibody, Cntnap2 antibody, cntnap2b antibody, cntnap2 antibody
    背景
    Contacting-associated protein 2 (Caspr2) is a member of the neurexin superfamily that mediates nervous system cell-cell interactions. The C-terminal region of Caspr2 participates in the association with Kv1.1, Kv1.2 and their Kv-beta-2 subunit. Expression of Caspr2 is regulated directly by transcription factor FOXP2. Disruption or decreased expression of Caspr2 probably leads to a disturbed distribution of potassium channels in the nervous system. Mutations in the Caspr2 gene have been linked to many diseases such as focal epilepsy, autism spectrum disorder and cortical dysplasia-focal epilepsy syndrome (CDFES).
    UniProt
    Q9UHC6
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