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CD42a 抗体 (FITC)

GP9 适用: 人, 犬 FACS 宿主: 小鼠 Monoclonal GR-P FITC
产品编号 ABIN1981888
发货至: 中国
  • 抗原 See all CD42a (GP9) 抗体
    CD42a (GP9) (Glycoprotein IX (Platelet) (GP9))
    适用
    • 56
    • 11
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 犬
    宿主
    • 40
    • 19
    小鼠
    克隆类型
    • 42
    • 17
    单克隆
    标记
    • 24
    • 8
    • 6
    • 5
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD42a antibody is conjugated to FITC
    应用范围
    • 25
    • 21
    • 19
    • 13
    • 12
    • 6
    • 5
    • 2
    • 2
    • 1
    Flow Cytometry (FACS)
    特异性
    The mouse monoclonal antibody GR-P (also known as GRP-P) recognizes an extracellular epitope of CD42a (glycoprotein 9), a 22 kDa transmembrane protein constitutively expressed on megakaryocytes and platelets.
    交叉反应 (详细)
    Human, Canine (Dog)
    纯化方法
    Purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
    免疫原
    Human acute lymphoblastic leukemia cells
    克隆位点
    GR-P
    亚型
    IgG1
    Top Product
    Discover our top product GP9 Primary Antibody
  • 应用备注
    Flow cytometry: The reagent is designed for analysis of human blood cells using 4 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests.
    说明

    The purified antibody is conjugated with Fluorescein isothiocyanate (FITC) under optimum conditions. The reagent is free of unconjugated FITC and adjusted for direct use. No reconstitution is necessary.

    限制
    仅限研究用
  • 缓冲液
    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Do not freeze. Avoid prolonged exposure to light.
    Do not use after expiration date stamped on vial label.
    Short-term exposure to room temperature should not affect the quality of the reagent. However, if reagent is stored under any conditions other than those specified, the conditions must be verified by the user.
    储存条件
    4 °C
    储存方法
    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • Din, Aftab, Jubb, Carnegy, Lyall, Sarma, Newby, Flapan: "Effect of moderate walnut consumption on lipid profile, arterial stiffness and platelet activation in humans." in: European journal of clinical nutrition, Vol. 65, Issue 2, pp. 234-9, (2011) (PubMed).

    Harding, Din, Sarma, Josephs, Fox, Newby: "Promotion of proinflammatory interactions between platelets and monocytes by unfractionated heparin." in: Heart (British Cardiac Society), Vol. 92, Issue 11, pp. 1635-8, (2006) (PubMed).

    Brown, Clarke, Magowan, Sanderson, Savill: "Constitutive death of platelets leading to scavenger receptor-mediated phagocytosis. A caspase-independent cell clearance program." in: The Journal of biological chemistry, Vol. 275, Issue 8, pp. 5987-96, (2000) (PubMed).

  • 抗原
    CD42a (GP9) (Glycoprotein IX (Platelet) (GP9))
    别名
    CD42a (GP9 产品)
    别名
    cd42a antibody, gpix antibody, GP9 antibody, GPIX antibody, Cd42 antibody, CD42a antibody, glycoprotein IX platelet antibody, glycoprotein IX platelet L homeolog antibody, glycoprotein IX (platelet) antibody, glycoprotein 9 (platelet) antibody, GP9 antibody, gp9.L antibody, Gp9 antibody
    背景
    Glycoprotein IX platelet,CD42a, also known as glycoprotein 9 (GPIX), composes together with GPIb alpha, GPIb beta and GPV the GPIb-IX-V receptor complex critical in the process of platelet-rich thrombus formation by tethering the platelet to a thrombogenic surface. CD42b binds to von Willebrand factor (VWF) exposed at a site of vascular injury, as well as to thrombin, coagulation factors XI and XII, high molecular wight kininogen, TSP-1, integrin Mac-1 and P-selectin. Defects in the gene encoding CD42a are a cause of Bernard-Soulier syndrome, also known as giant platelet disease. These patients have unusually large platelets and have a clinical bleeding tendency.,GPIX, GP9
    基因ID
    2815
    UniProt
    P14770
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