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- 抗原 See all LRRC32 抗体
- LRRC32 (Leucine Rich Repeat Containing 32 (LRRC32))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This LRRC32 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 特异性
- The mouse monoclonal antibody GARP5 recognizes GARP / LRRC32, an approximately 80 kDa glycoprotein expressed e.g. on the surface of megakaryocytes, platelets and activated Treg cells.
- 交叉反应 (详细)
- Human
- 纯化方法
- Purified by protein-A affinity chromatography.
- 纯度
- > 95 % (by SDS-PAGE)
- 免疫原
- Purified human sGARP protein
- 克隆位点
- GARP5
- 亚型
- IgG1
- Top Product
- Discover our top product LRRC32 Primary Antibody
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- 应用备注
- Western blotting: Recommended dilution: 1-2 μg/mL, positive control: human thrombocytes, reducing conditions
- 限制
- 仅限研究用
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- 浓度
- 1 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Do not freeze. Do not use after expiration date stamped on vial label.
- 储存条件
- 4 °C
- 储存方法
- Store at 2-8°C. Do not freeze.
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GARP regulates the bioavailability and activation of TGF?." in: Molecular biology of the cell, Vol. 23, Issue 6, pp. 1129-39, (2012) (PubMed).
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GARP regulates the bioavailability and activation of TGF?." in: Molecular biology of the cell, Vol. 23, Issue 6, pp. 1129-39, (2012) (PubMed).
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- 抗原
- LRRC32 (Leucine Rich Repeat Containing 32 (LRRC32))
- 别名
- GARP / LRRC32 (LRRC32 产品)
- 别名
- D11S833E antibody, GARP antibody, AI426318 antibody, D11S833Eh antibody, D7H11S833E antibody, EG434215 antibody, Garp antibody, leucine rich repeat containing 32 antibody, LRRC32 antibody, Lrrc32 antibody
- 背景
- Leucine rich repeat containing 32,GARP (glycoprotein A repetitions predominant protein), also known as garpin or LRRC32 (leucin-rich repeat containing protein 32) is an approximately 80 kDa transmembrane glycoprotein detected on the surface of megakaryocytes, platelets, and activated Treg cells. It binds to the latency-associated peptide (LAP) domain of pro-TGF beta and regulates its storage and activation. The expression of GARP on Treg cells seems to be necessary for their suppressive functions.,GARP, D11S833E
- 基因ID
- 2615
- UniProt
- Q14392
- 途径
- Activated T Cell Proliferation
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