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LRRC32 抗体

LRRC32 适用: 人 WB 宿主: 小鼠 Monoclonal GARP5 unconjugated
产品编号 ABIN1981876
发货至: 中国
  • 抗原 See all LRRC32 抗体
    LRRC32 (Leucine Rich Repeat Containing 32 (LRRC32))
    适用
    • 26
    • 10
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    • 1
    宿主
    • 20
    • 12
    • 1
    • 1
    小鼠
    克隆类型
    • 21
    • 13
    单克隆
    标记
    • 18
    • 7
    • 4
    • 2
    • 2
    • 1
    This LRRC32 antibody is un-conjugated
    应用范围
    • 17
    • 15
    • 14
    • 6
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    • 1
    Western Blotting (WB)
    特异性
    The mouse monoclonal antibody GARP5 recognizes GARP / LRRC32, an approximately 80 kDa glycoprotein expressed e.g. on the surface of megakaryocytes, platelets and activated Treg cells.
    交叉反应 (详细)
    Human
    纯化方法
    Purified by protein-A affinity chromatography.
    纯度
    > 95 % (by SDS-PAGE)
    免疫原
    Purified human sGARP protein
    克隆位点
    GARP5
    亚型
    IgG1
    Top Product
    Discover our top product LRRC32 Primary Antibody
  • 应用备注
    Western blotting: Recommended dilution: 1-2 μg/mL, positive control: human thrombocytes, reducing conditions
    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Do not freeze. Do not use after expiration date stamped on vial label.
    储存条件
    4 °C
    储存方法
    Store at 2-8°C. Do not freeze.
  • Wang, Zhu, Dong, Shi, Lu, Springer: "GARP regulates the bioavailability and activation of TGF?." in: Molecular biology of the cell, Vol. 23, Issue 6, pp. 1129-39, (2012) (PubMed).

  • 抗原
    LRRC32 (Leucine Rich Repeat Containing 32 (LRRC32))
    别名
    GARP / LRRC32 (LRRC32 产品)
    背景
    Leucine rich repeat containing 32,GARP (glycoprotein A repetitions predominant protein), also known as garpin or LRRC32 (leucin-rich repeat containing protein 32) is an approximately 80 kDa transmembrane glycoprotein detected on the surface of megakaryocytes, platelets, and activated Treg cells. It binds to the latency-associated peptide (LAP) domain of pro-TGF beta and regulates its storage and activation. The expression of GARP on Treg cells seems to be necessary for their suppressive functions.,GARP, D11S833E
    基因ID
    2615
    UniProt
    Q14392
    途径
    Activated T Cell Proliferation
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