Fc gamma RII (CD32) 抗体
(4 references)-
- 抗原 See all Fc gamma RII (CD32) 抗体
- Fc gamma RII (CD32)
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- 非结合性
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应用范围
- Flow Cytometry (FACS), Cytometry by Time of Flight (CyTOF)
- 特异性
- The mouse monoclonal antibody 3D3 recognizes an extracellular epitope of CD32, a 40 kDa polymorphic transmembrane glycoprotein serving as the low affinity receptor for aggregated IgG. This antibody recognizes CD32 isoforms on B cells of all donors, but on platelets, monocytes, and granulocytes of only some donors (131R variant, but not 131H variant).
- 交叉反应 （详细）
- Human
- 纯化方法
- Purified by protein-A affinity chromatography.
- 纯度
- > 95 % (by SDS-PAGE)
- 免疫原
- purified glycosylated recombinant human FcgammaRIIa2
- 克隆位点
- 3D3
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product CD32 Primary Antibody
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anti-Fc gamma RII (CD32) antibody
CD32 适用: 人 FACS, WB, IHC, IP, IHC (p) 宿主: 小鼠 Monoclonal 6D11 unconjugated
anti-Fc gamma RII (CD32) (AA 201-300) antibodyCD32 适用: 人 FACS, WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Fc gamma RII (CD32) antibody (PE)CD32 适用: 人 FACS 宿主: 小鼠 Monoclonal 3D3 PE
anti-Fc gamma RII (CD32) (AA 69-309) antibodyCD32 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fc gamma RII (CD32) antibody (PE)GMP Grade CD32 适用: 人 FACS 宿主: 小鼠 Monoclonal IV-3 PE
anti-Fc gamma RII (CD32) antibody (FITC)GMP Grade CD32 适用: 人 FACS 宿主: 小鼠 Monoclonal IV-3 FITC
anti-Fc gamma RII (CD32) (AA 36-229) antibodyCD32 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Fc gamma RII (CD32) antibodyCD32 适用: 人, 犬, 猕猴, Pig FACS, IP, IHC (fro), Func 宿主: 小鼠 Monoclonal AT10 unconjugated
anti-Fc gamma RII (CD32) antibody (PE)CD32 适用: Cow, 绵羊 FACS 宿主: 小鼠 Monoclonal CCG36 PE
anti-Fc gamma RII (CD32) antibody (FITC)CD32 适用: 人 FACS 宿主: 小鼠 Monoclonal 3D3 FITC
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- 应用备注
- Flow cytometry: Recommended dilution: 2-6 μg/mL.
- 限制
- 仅限研究用
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- 浓度
- 1 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Do not freeze. Do not use after expiration date stamped on vial label.
- 储存条件
- 4 °C
- 储存方法
- Store at 2-8°C. Do not freeze.
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: "Chronic lymphocytic leukemia cells are activated and proliferate in response to specific T helper cells." in: Cell reports, Vol. 4, Issue 3, pp. 566-77, (2013) (PubMed).
: "A novel subset of NK cells expressing high levels of inhibitory FcgammaRIIB modulating antibody-dependent function." in: Journal of leukocyte biology, Vol. 84, Issue 6, pp. 1511-20, (2008) (PubMed).
: "Activating and inhibitory IgG Fc receptors on human DCs mediate opposing functions." in: The Journal of clinical investigation, Vol. 115, Issue 10, pp. 2914-23, (2005) (PubMed).
: "A new set of monoclonal antibodies against human Fc gamma RII (CD32) and Fc gamma RIII (CD16): characterization and use in various assays." in: Hybridoma, Vol. 16, Issue 6, pp. 519-28, (1998) (PubMed).
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: "Chronic lymphocytic leukemia cells are activated and proliferate in response to specific T helper cells." in: Cell reports, Vol. 4, Issue 3, pp. 566-77, (2013) (PubMed).
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- 抗原
- Fc gamma RII (CD32)
- 别名
- CD32 (CD32 产品)
- 别名
- CD32 antibody, CD32B antibody, FCG2 antibody, FCGR2 antibody, IGFR2 antibody, FCGR2B antibody, AI528646 antibody, F630109E10Rik antibody, Fc[g]RII antibody, FcgRII antibody, Fcgr2 antibody, Fcgr2a antibody, Fcr-2 antibody, Fcr-3 antibody, Ly-17 antibody, Ly-m20 antibody, LyM-1 antibody, Lym-1 antibody, FCRII antibody, FcRII antibody, Fc fragment of IgG receptor IIb antibody, Fc receptor, IgG, low affinity IIb antibody, FCGR2B antibody, Fcgr2b antibody
- 背景
- Fc fragment of IgG receptor IIa,CD32 (FcgammaRII) is a low affinity receptor for aggregated IgG. It is strongly expressed on monocytes, granulocytes, myeloid and myeloblastic cell lines, and weakly on B cells, CD34+ bone marrow cells, and resting and activated platelets. After binding its ligand, CD32 induces IgG-mediated phagocytosis and oxidative burst in monocytes and neutrophils, whereas in B cells it mediates a negative signal. This polymorphic transmembrane glycoprotein is expressed not only in the activating (CD32a) and inhibitory isoform (CD32b), but also in individual variants with differing avidities for IgG subtypes (e.g. the CD32a131R and CD32a131H allotypes).,FCG2, FCGR2A, IGFR2
- 基因ID
- 2212
- UniProt
- P12318
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