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- 抗原 See all CCR7 抗体
- CCR7 (Chemokine (C-C Motif) Receptor 7 (CCR7))
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适用
- 小鼠
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宿主
- 大鼠
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克隆类型
- 单克隆
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标记
- This CCR7 antibody is conjugated to PE
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应用范围
- Flow Cytometry (FACS)
- 特异性
- The rat monoclonal antibody 4B12 recognizes an extracellular epitope of murine CD197 / CCR7 (chemokine receptor 7), a 43 kDa G-protein-coupled receptor for chemokines CCL19 and CCL21.
- 交叉反应 (详细)
- Mouse
- 纯化方法
- Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
- 免疫原
- Murine CD197-transfected RBL-2H3 cells
- 克隆位点
- 4B12
- 亚型
- IgG2a kappa
- Top Product
- Discover our top product CCR7 Primary Antibody
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- 应用备注
- Flow cytometry: Recommended dilution: 1-5 μg/mL.
- 说明
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The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography.
- 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
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Do not freeze. Avoid prolonged exposure to light.
Do not use after expiration date stamped on vial label.
Short-term exposure to room temperature should not affect the quality of the reagent. However, if reagent is stored under any conditions other than those specified, the conditions must be verified by the user. - 储存条件
- 4 °C
- 储存方法
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
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Unique T cells with unconventional cytokine profiles induced in the livers of mice during Schistosoma mansoni infection." in: PLoS ONE, Vol. 8, Issue 12, pp. e82698, (2013) (PubMed).
: "NLRP10 is a NOD-like receptor essential to initiate adaptive immunity by dendritic cells." in: Nature, Vol. 484, Issue 7395, pp. 510-3, (2012) (PubMed).
: "Annexin-1-deficient dendritic cells acquire a mature phenotype during differentiation." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 23, Issue 4, pp. 985-96, (2009) (PubMed).
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Unique T cells with unconventional cytokine profiles induced in the livers of mice during Schistosoma mansoni infection." in: PLoS ONE, Vol. 8, Issue 12, pp. e82698, (2013) (PubMed).
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- 抗原
- CCR7 (Chemokine (C-C Motif) Receptor 7 (CCR7))
- 别名
- CD197 / CCR7 (CCR7 产品)
- 别名
- zgc:165629 antibody, ccr7-a antibody, CD197 antibody, Cdw197 antibody, Cmkbr7 antibody, EBI1 antibody, Ebi1h antibody, BLR2 antibody, CDw197 antibody, CMKBR7 antibody, chemokine (C-C motif) receptor 7 antibody, C-C motif chemokine receptor 7 antibody, C-C motif chemokine receptor 7 L homeolog antibody, ccr7 antibody, CCR7 antibody, ccr7.L antibody, Ccr7 antibody
- 背景
- Chemokine (C-C motif) receptor 7,CD197 / CCR7 (chemokine receptor 7) is a seven membrane-spanning protein serving as a receptor for chemokines CCL19 and CCL21. It is expressed on most naive T cells, some hematopoietic stem cells, mature dendritic cells, NK cells and some memory T cells and B cells subsets. CD197 plays important roles in development of thymocytes, and regulating the recirculation and homing of lymphocytes and dendritic cells to secondary lymphoid organs.,CCR7, CC-CKR-7, EBI1
- 基因ID
- 12775
- UniProt
- P47774
- 途径
- Regulation of Actin Filament Polymerization, Positive Regulation of Immune Effector Process
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