MSK1 抗体 (Ser376)
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- 抗原 See all MSK1 (RPS6KA5) 抗体
- MSK1 (RPS6KA5) (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 5 (RPS6KA5))
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抗原表位
- Ser376
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MSK1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 特异性
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. MSK1 antibody AP02710PU detects endogenous levels of total MSK1 protein.
- 纯化方法
- Immunoaffinity chromatography.
- 免疫原
- The antiserum was produced against synthesized non-phosphopeptide derived from human MSK1 around the phosphorylation site of serine 376 (G-Y-Sp-F-V).
- Top Product
- Discover our top product RPS6KA5 Primary Antibody
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anti-Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 5 (RPS6KA5) (AA 224-367) antibody
RPS6KA5 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 5 (RPS6KA5) (AA 271-370) antibodyRPS6KA5 适用: 人 WB, ELISA, IF, PLA 宿主: 小鼠 Monoclonal 2B11 unconjugated
anti-Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 5 (RPS6KA5) (pSer376) antibodyRPS6KA5 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 5 (RPS6KA5) (AA 540-665) antibodyRPS6KA5 适用: 人, 小鼠, 大鼠 WB, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 5 (RPS6KA5) (AA 1-802) antibodyRPS6KA5 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 5 (RPS6KA5) antibodyRPS6KA5 适用: 人 ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal 1G7 unconjugated
anti-Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 5 (RPS6KA5) (Ser212) antibodyRPS6KA5 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 5 (RPS6KA5) (Internal Region) antibodyRPS6KA5 适用: 人, 小鼠 WB, IF, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 5 (RPS6KA5) (pSer360) antibodyRPS6KA5 适用: 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 5 (RPS6KA5) (pSer212) antibodyRPS6KA5 适用: 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Suitable for use in in Western blot (1: 500-1: 1000).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- -20 °C
- 储存方法
- Store the antibody (in aliquots) at -20 °C.
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- 抗原
- MSK1 (RPS6KA5) (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 5 (RPS6KA5))
- 别名
- RPS6KA5 / MSK1 (RPS6KA5 产品)
- 别名
- MSK1 antibody, MSPK1 antibody, RLPK antibody, 3110005L17Rik antibody, 6330404E13Rik antibody, AI854034 antibody, Msk1 antibody, ribosomal protein S6 kinase A5 antibody, ribosomal protein S6 kinase, polypeptide 5 antibody, RPS6KA5 antibody, Rps6ka5 antibody
- 背景
- MSK1 is a mitogen and stress activated protein kinase 1 which belongs to the AGC family of kinases and is related in structure to the ribosomal p70 S6 kinase subfamily. MSK1 can be activated by ERK1/2 and SAPK2/p38 MAP kinase. It is also known to be required for the phosphorylation of CREB, ATF1 H3 and HMG14 in response to mitogen and stress. Similar to RSK, MSK1 contains two kinase domains (N term and a C term). Once phosphorylated on Thr581 and Ser360 by ERK1/2 and SAPK2/p38, MSK1 autophosphorylate on at least 5 sites. Of these autophosphorylation sites Ser212 and Ser376 get phosphorylated by the C terminal kinase domain of MSK1 which is essential for the catalytic activity of the N terminal kinase domain.Synonyms: 90 kDa ribosomal protein S6 kinase 5, Nuclear mitogen- and stress-activated protein kinase 1, RSK-like protein kinase, RSKL, Ribosomal protein S6 kinase alpha-5
- 基因ID
- 9252
- NCBI登录号
- NP_004746
- UniProt
- O75582
- 途径
- MAPK Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
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