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CDKN1B 抗体 (Ser10)

CDKN1B 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN197350
发货至: 中国
  • 抗原 See all CDKN1B 抗体
    CDKN1B (Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1) (CDKN1B))
    抗原表位
    • 26
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    • 10
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    Ser10
    适用
    • 246
    • 114
    • 102
    • 26
    • 6
    • 6
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 212
    • 47
    • 2
    • 1
    • 1
    克隆类型
    • 203
    • 60
    多克隆
    标记
    • 135
    • 18
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    This CDKN1B antibody is un-conjugated
    应用范围
    • 183
    • 116
    • 62
    • 60
    • 49
    • 41
    • 34
    • 26
    • 22
    • 16
    • 16
    • 11
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    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody detects endogenous levels of total p27Kip1 protein.
    纯化方法
    Immunoaffinity Chromatography.
    免疫原
    The antiserum was produced against synthesized non-phosphopeptide derived from human p27Kip1 around the phosphorylation site of serine 10 (N-G-Sp-P-S).
    Top Product
    Discover our top product CDKN1B Primary Antibody
  • 应用备注
    Western blot: 1/500-1/1000. Immunohistochemistry: 1/50-1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide as preservative and 50 % Glycerol as stabilizer.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store the antibody (in aliquots) at -20 °C.
  • 抗原
    CDKN1B (Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1) (CDKN1B))
    别名
    CDKN1B / KIP1 (CDKN1B 产品)
    背景
    P27 is a cyclin dependent kinase inhibitor (CKI) which controls G1/S phase transition in the cell cycle. p27 prevents cell cycle progression by inhibiting the activity of cyclin E-Cdk2 and cyclin D-Cdk4/6, thus preventing E2F activation and S phase progression. Low p27 levels and/or cytosolic mis-localisation have been associated with the development of lung, breast, colon, oesophagus, and prostate tumours.Synonyms: Cyclin-dependent kinase inhibitor 1B, Cyclin-dependent kinase inhibitor p27, p27Kip1
    基因ID
    1027
    NCBI登录号
    NP_004055
    UniProt
    P46527
    途径
    Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Negative Regulation of Hormone Secretion, Sensory Perception of Sound, Mitotic G1-G1/S Phases, DNA Replication, Positive Regulation of Endopeptidase Activity, Synthesis of DNA, Autophagy
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