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PDPK1 抗体 (Ser241)

PDPK1 适用: 人, 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN197100
发货至: 中国
  • 抗原 See all PDPK1 抗体
    PDPK1 (3-phosphoinositide Dependent Protein Kinase-1 (PDPK1))
    抗原表位
    • 24
    • 22
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    • 8
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    Ser241
    适用
    • 174
    • 120
    • 85
    • 12
    • 6
    • 6
    • 6
    • 5
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    人, 小鼠
    宿主
    • 172
    • 18
    • 1
    克隆类型
    • 166
    • 25
    多克隆
    标记
    • 82
    • 10
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    • 7
    • 5
    • 5
    • 5
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    • 5
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    • 4
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    This PDPK1 antibody is un-conjugated
    应用范围
    • 141
    • 66
    • 53
    • 53
    • 28
    • 26
    • 12
    • 8
    • 8
    • 7
    • 7
    • 5
    • 3
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    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    PDK1 antibody detects endogenous levels of total PDK1 protein.
    纯化方法
    Affinity chromatography
    免疫原
    Synthetic non-phosphopeptide derived from human PDK1 around the phosphorylation site of serine 241(A-N-SP-F-V).
    Top Product
    Discover our top product PDPK1 Primary Antibody
  • 应用备注
    Western Blot: 1/500approx. 1/1000. Immunohistochemistry: 1/50approx. 1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS (without Mg2+ and Ca2+), pH 7.4 containing 150 mM NaCl, 0.02 % Sodium Azide as preservative and 50 % Glycerol as stabilizer.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store the antibody undiluted (in aliquots) at -20 °C.
  • 抗原
    PDPK1 (3-phosphoinositide Dependent Protein Kinase-1 (PDPK1))
    别名
    PDPK1 (PDPK1 产品)
    别名
    pdpk1 antibody, MGC82080 antibody, PDK1 antibody, PDPK2 antibody, PRO0461 antibody, Pdk1 antibody, zgc:153787 antibody, 3'-phosphoinositide-dependent protein kinase 1 antibody, 3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASE 1 antibody, ATPDK1 antibody, AtPDK1 antibody, T32M21.110 antibody, T32M21_110 antibody, zgc:77318 antibody, 3-phosphoinositide dependent protein kinase 1 antibody, 3-phosphoinositide dependent protein kinase 1 L homeolog antibody, 3-phosphoinositide dependent protein kinase-1 antibody, 3-phosphoinositide dependent protein kinase 1a antibody, 3-phosphoinositide-dependent protein kinase 1 antibody, 3'-phosphoinositide-dependent protein kinase 1 antibody, 3-phosphoinositide dependent protein kinase 1b antibody, PDPK1 antibody, pdpk1.L antibody, pdpk1 antibody, Pdpk1 antibody, pdpk1a antibody, LOC100380750 antibody, pdk-1 antibody, PDK1 antibody, pdpk1b antibody
    背景
    Phosphorylates and activates not only PKB/AKT, but also PKA, PKC-zeta, RPS6KA1 and RPS6KB1. May play a general role in signaling processes and in development (By similarity). Isoform 3 is catalytically inactive.Synonyms: 3-phosphoinositide-dependent proteinkinase 1, PDK-1, PDK1, PDPK1, hPDK1
    基因ID
    5170
    NCBI登录号
    NP_002604
    UniProt
    O15530
    途径
    PI3K-Akt Signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Regulation of Cell Size, Skeletal Muscle Fiber Development, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals
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