BIM 抗体 (pSer65, pSer69)
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- 抗原 See all BIM (BCL2L11) 抗体
- BIM (BCL2L11) (BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11))
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抗原表位
- pSer65, pSer69
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This BIM antibody is un-conjugated
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应用范围
- Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- This antibody detects endogenous levels of BIM only when phosphorylated at Serine 69.
- 纯化方法
- Affinity Chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatogramphy using non-phosphopeptide corresponding to the phosphorylation site.
- 免疫原
- The antiserum was produced against synthesized phosphopeptide derived from Human BIM around the phosphorylation site of Serine 69 (Serine 65 in the Mouse sequence) (P-A-SP-P-G).
- Top Product
- Discover our top product BCL2L11 Primary Antibody
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anti-BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11) (AA 2-120) antibody
BCL2L11 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11) (pSer87) antibodyBCL2L11 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11) (AA 1-198) antibodyBCL2L11 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11) antibodyBCL2L11 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11) (AA 134-160) antibodyBCL2L11 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB22105 unconjugated
anti-BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11) (Middle Region) antibodyBCL2L11 适用: 人 WB, EIA 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11) (AA 51-150) antibodyBCL2L11 适用: 人, 小鼠 WB, ELISA, IHC (p), FACS 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11) (pSer69) antibodyBCL2L11 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11) antibody (Alkaline Phosphatase (AP))BCL2L11 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal Alkaline Phosphatase (AP)
anti-BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11) antibody (Biotin)BCL2L11 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal Biotin
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- 应用备注
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Immunofluorescence: 1/100-1/200. Immunohistochemistry on Paraffin-Embedded Sections: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- -20 °C
- 储存方法
- Store the antibody (in aliquots) at -20 °C.
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- 抗原
- BIM (BCL2L11) (BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11))
- Abstract
- BCL2L11 产品
- 别名
- bim antibody, BAM antibody, BIM antibody, BOD antibody, 1500006F24Rik antibody, Bim antibody, Bod antibody, BimL antibody, BIMEL antibody, BCL2-like 11 antibody, BCL2 like 11 antibody, BCL2-like 11 (apoptosis facilitator) antibody, bcl2l11 antibody, BCL2L11 antibody, Bcl2l11 antibody
- 背景
- Bim, Bcl-2 interacting mediator of cell death, is a pro-apoptotic protein belonging to the Bcl2 family of proteins containing a Bcl2 homology domain 3 (BH3). It is proapoptotic and exerts its effects by interacting with prosurvival members of the Bcl2 family like Bcl2, BclxL and Bclw. Bim is sequestered in an inactive conformation through binding to the microtubule-associated dynein motor complex. Certain apoptotic stimuli release Bim from microtubules, allowing inhibitory binding to anti-apoptotic Bcl-2 family members and subsequent iniation of apoptosis.Synonyms: BCL2L11, BIM, Bcl2-L-11, Bcl2-interacting mediator of cell death, BimEL, BimL, BimS
- 基因ID
- 10018
- NCBI登录号
- NP_001191035
- UniProt
- O43521
- 途径
- PI3K-Akt Signaling, Neurotrophin Signaling Pathway, Tube Formation, Positive Regulation of Endopeptidase Activity
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