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PRKDC 抗体 (pThr2609)

PRKDC 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN196899
发货至: 中国
  • 抗原 See all PRKDC 抗体
    PRKDC (Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC))
    抗原表位
    • 26
    • 13
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    • 7
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    • 5
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    pThr2609
    适用
    • 162
    • 86
    • 47
    • 5
    • 2
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    • 2
    • 1
    宿主
    • 151
    • 22
    • 3
    • 2
    克隆类型
    • 148
    • 30
    多克隆
    标记
    • 90
    • 11
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    This PRKDC antibody is un-conjugated
    应用范围
    • 79
    • 67
    • 56
    • 30
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    • 7
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    Western Blotting (WB)
    特异性
    DNA PKcs (phospho-Thr2609) antibody detects endogenous levels of DNA PKcs only when phosphorylated at threonine 2609.
    纯化方法
    Immunoaffinity chromatography using epitope-specific phosphopeptide.
    免疫原
    The antiserum was produced against synthesized phosphopeptide derived from human DNA PKcs around the phosphorylation site of threonine 2609 (V-E-TP-Q-A).
    Top Product
    Discover our top product PRKDC Primary Antibody
  • 应用备注
    Suitable for use in Suitable for use in Western blot (1: 500-1: 1000).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store the antibody (in aliquots) at -20 °C.
  • 抗原
    PRKDC (Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC))
    别名
    DNA-PKcs / PRKDC / XRCC7 (PRKDC 产品)
    背景
    DNA PK is the key component of the non-homologous end-joining (NHEJ) pathway of DSB repair in mammalian cells. DNA PK consists of a heterodimeric DNA-binding subunit (Ku70/80) and an approximately 465 kDa catalytic subunit (DNA PKcs). DNA PKcs is a serine/threonine protein kinase whose activity is greatly stimulated by its recruitment to DNA breaks by the Ku heterodimer.Synonyms: DNA-dependent protein kinase catalytic subunit, DNPK1, HYRC, HYRC1, p460
    基因ID
    5591
    NCBI登录号
    NP_001075109
    UniProt
    P78527
    途径
    DNA Damage Repair, Production of Molecular Mediator of Immune Response
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