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PAR1 抗体

F2R 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1944818
发货至: 中国
  • 抗原 See all PAR1 (F2R) 抗体
    PAR1 (F2R) (Coagulation Factor II (thrombin) Receptor (F2R))
    适用
    • 75
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    宿主
    • 68
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    克隆类型
    • 71
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    多克隆
    标记
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    This PAR1 antibody is un-conjugated
    应用范围
    • 59
    • 35
    • 13
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    • 5
    • 3
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    Western Blotting (WB)
    亚型
    IgG1
    Top Product
    Discover our top product F2R Primary Antibody
  • 应用备注
    WB: 1:500- 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
    储存条件
    4 °C,-20 °C
  • Zania, Gourni, Aplin, Nicosia, Flordellis, Maragoudakis, Tsopanoglou: "Parstatin, the cleaved peptide on proteinase-activated receptor 1 activation, is a potent inhibitor of angiogenesis." in: The Journal of pharmacology and experimental therapeutics, Vol. 328, Issue 2, pp. 378-89, (2009) (PubMed).

    Kahn, Nakanishi-Matsui, Shapiro, Ishihara, Coughlin: "Protease-activated receptors 1 and 4 mediate activation of human platelets by thrombin." in: The Journal of clinical investigation, Vol. 103, Issue 6, pp. 879-87, (1999) (PubMed).

    Shapiro, Trejo, Zeng, Coughlin: "Role of the thrombin receptor's cytoplasmic tail in intracellular trafficking. Distinct determinants for agonist-triggered versus tonic internalization and intracellular localization." in: The Journal of biological chemistry, Vol. 271, Issue 51, pp. 32874-80, (1997) (PubMed).

  • 抗原
    PAR1 (F2R) (Coagulation Factor II (thrombin) Receptor (F2R))
    别名
    Thrombin Receptor (F2R 产品)
    别名
    CF2R antibody, HTR antibody, PAR-1 antibody, PAR1 antibody, TR antibody, Par1 antibody, TRGPC antibody, AI482343 antibody, Cf2r antibody, ThrR antibody, Par-1 antibody, f2r-a antibody, par1 antibody, coagulation factor II thrombin receptor antibody, coagulation factor II (thrombin) receptor antibody, coagulation factor 2 (thrombin) receptor L homeolog antibody, F2R antibody, F2r antibody, f2r.L antibody
    背景
    High affinity receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation and in vascular development.
    分子量
    47441 Da
    基因ID
    2149
    UniProt
    P25116
    途径
    Nuclear Receptor Transcription Pathway, Skeletal Muscle Fiber Development, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus
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