Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02 % sodium azide and 50 % glycerol.
储存液
Sodium azide
注意事项
WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
储存条件
4 °C,-20 °C
Ebisawa, Uchiyama, Kajimura, Kamei, Shibui, Kim, Kudo, Iwase, Sugishita, Jodoi, Ikeda, Ozeki, Watanabe, Sekimoto, Katoh, Yamada, Toyoshima, Okawa, Takahashi, Yamauchi: "Genetic polymorphisms of human melatonin 1b receptor gene in circadian rhythm sleep disorders and controls." in: Neuroscience letters, Vol. 280, Issue 1, pp. 29-32, (2000) (PubMed).
Reppert, Godson, Mahle, Weaver, Slaugenhaupt, Gusella: "Molecular characterization of a second melatonin receptor expressed in human retina and brain: the Mel1b melatonin receptor." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 92, Issue 19, pp. 8734-8, (1995) (PubMed).
High affinity receptor for melatonin. Likely to mediates the reproductive and circadian actions of melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity.