USP11 抗体 (N-Term)
-
- 抗原 See all USP11 抗体
- USP11 (Ubiquitin Specific Peptidase 11 (USP11))
-
抗原表位
- AA 32-300, N-Term
-
适用
- 人
-
宿主
- 小鼠
-
克隆类型
- 单克隆
-
标记
- This USP11 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Flow Cytometry (FACS)
- 纯化方法
- This antibody is purified through a protein G column, followed by dialysis against PBS.
- 免疫原
- This USP11 antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 32-300 amino acids from the N-terminal region of human USP11.
- 克隆位点
- 1220CT620-193-189
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product USP11 Primary Antibody
-
-
- 应用备注
- WB: 1:1000. FC: 1:25
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 缓冲液
- Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 有效期
- 6 months
-
-
The deubiquitinating enzyme USP11 controls an IkappaB kinase alpha (IKKalpha)-p53 signaling pathway in response to tumor necrosis factor alpha (TNFalpha)." in: The Journal of biological chemistry, Vol. 282, Issue 47, pp. 33943-8, (2007) (PubMed).
: "BRCA2 is ubiquitinated in vivo and interacts with USP11, a deubiquitinating enzyme that exhibits prosurvival function in the cellular response to DNA damage." in: Molecular and cellular biology, Vol. 24, Issue 17, pp. 7444-55, (2004) (PubMed).
: "Structural and functional characterization of the USP11 deubiquitinating enzyme, which interacts with the RanGTP-associated protein RanBPM." in: The Biochemical journal, Vol. 367, Issue Pt 1, pp. 87-95, (2002) (PubMed).
: "A ubiquitin C-terminal hydrolase gene on the proximal short arm of the X chromosome: implications for X-linked retinal disorders." in: Human molecular genetics, Vol. 5, Issue 4, pp. 533-8, (1996) (PubMed).
: "
-
The deubiquitinating enzyme USP11 controls an IkappaB kinase alpha (IKKalpha)-p53 signaling pathway in response to tumor necrosis factor alpha (TNFalpha)." in: The Journal of biological chemistry, Vol. 282, Issue 47, pp. 33943-8, (2007) (PubMed).
-
- 抗原
- USP11 (Ubiquitin Specific Peptidase 11 (USP11))
- 别名
- USP11 (USP11 产品)
- 别名
- USP11 antibody, DKFZp459L098 antibody, UHX1 antibody, 6230415D12Rik antibody, mKIAA4085 antibody, Uhx1 antibody, ubiquitin specific peptidase 11 antibody, universal stress protein antibody, USP11 antibody, RR_RS19935 antibody, Usp11 antibody
- 背景
- Protease that can remove conjugated ubiquitin from target proteins and polyubiquitin chains. Inhibits the degradation of target proteins by the proteasome. Plays a role in the regulation of pathways leading to NF-kappa-B activation. Plays a role in the regulation of DNA repair after double-stranded DNA breaks.
- 分子量
- 109817
- 基因ID
- 8237
- UniProt
- P51784
-