SP1 抗体 (AA 1-250)
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- 抗原 See all SP1 抗体
- SP1 (Sp1 Transcription Factor (SP1))
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抗原表位
- AA 1-250
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This SP1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)
- 纯化方法
- This antibody is purified through a protein G column, followed by dialysis against PBS.
- 免疫原
- This SP1 antibody is generated from a mouse immunized with a recombination protein from the human SP1.
- 克隆位点
- 1326CT463-109-176
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product SP1 Primary Antibody
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- 应用备注
- IF: 1:25. WB: 1:1000. FC: 1:25
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 有效期
- 6 months
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Heterogeneous Sp1 mRNAs in human HepG2 cells include a product of homotypic trans-splicing." in: The Journal of biological chemistry, Vol. 275, Issue 48, pp. 38067-72, (2000) (PubMed).
: "Isolation of cDNA encoding transcription factor Sp1 and functional analysis of the DNA binding domain." in: Cell, Vol. 51, Issue 6, pp. 1079-90, (1988) (PubMed).
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Heterogeneous Sp1 mRNAs in human HepG2 cells include a product of homotypic trans-splicing." in: The Journal of biological chemistry, Vol. 275, Issue 48, pp. 38067-72, (2000) (PubMed).
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- 抗原
- SP1 (Sp1 Transcription Factor (SP1))
- 别名
- SP1 (SP1 产品)
- 别名
- fc18h09 antibody, zgc:85950 antibody, wu:fc18h09 antibody, SP1 antibody, 1110003E12Rik antibody, AA450830 antibody, AI845540 antibody, Sp1-1 antibody, sp1 transcription factor antibody, Sp1 transcription factor antibody, Sp1 transcription factor L homeolog antibody, trans-acting transcription factor 1 antibody, sp1 antibody, SP1 antibody, Sp1 antibody, sp1.L antibody
- 背景
- Transcription factor that can activate or repress transcription in response to physiological and pathological stimuli. Binds with high affinity to GC-rich motifs and regulates the expression of a large number of genes involved in a variety of processes such as cell growth, apoptosis, differentiation and immune responses. Highly regulated by post-translational modifications (phosphorylations, sumoylation, proteolytic cleavage, glycosylation and acetylation). Binds also the PDGFR- alpha G-box promoter. May have a role in modulating the cellular response to DNA damage. Implicated in chromatin remodeling. Plays a role in the recruitment of SMARCA4/BRG1 on the c-FOS promoter. Plays an essential role in the regulation of FE65 gene expression. In complex with ATF7IP, maintains telomerase activity in cancer cells by inducing TERT and TERC gene expression.
- 分子量
- 80693
- 基因ID
- 6667
- UniProt
- P08047
- 途径
- Regulation of Lipid Metabolism by PPARalpha, Myometrial Relaxation and Contraction
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