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Presenilin 2 抗体 (N-Term)

Name: Presenilin 2 抗体 (N-Term)
SKU: ABIN1944732
Availability: OutOfStock

PSEN2 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB30801 unconjugated

Western blot analysis of lysate from Hela cell line, using PSEN2(Presenilin-2 NTF subunit) Antibody (N-term) (ABIN1944732 and ABIN2838558). (Presenilin 2 抗体 (N-Term))

Flow cytometric analysis of Hela cells using PSEN2(Presenilin-2 NTF subunit) Antibody (N-term)(green, Cat(ABIN1944732 and ABIN2838558)) compared to an isotype control of rabbit IgG(blue). (Presenilin 2 抗体 (N-Term))

FACS

2 images

(4 references)

产品编号 ABIN1944732

发货至: 中国

Datasheet as PDF

抗原 See all Presenilin 2 (PSEN2) 抗体

Presenilin 2 (PSEN2) (Presenilin 2 (Alzheimer Disease 4) (PSEN2))
抗原表位
15

9

6

4

3

3

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 32-65, N-Term
适用
64

49

34

6

6

5

5

5

5

3

2

2

2

1

1

1
人
宿主
55

3

3

2

2
兔
Compatible Secondaries
克隆类型
62

3
多克隆
标记
35

4

3

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This Presenilin 2 antibody is un-conjugated
应用范围
47

20

14

13

11

9

3

3

1

1
Western Blotting (WB), Flow Cytometry (FACS)

纯化方法

This antibody is purified through a protein A column, followed by peptide affinity purification.

免疫原

This PSEN2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 32-65 amino acids from the N-terminal region of human PSEN2(Presenilin-2 NTF subunit).

克隆位点

RB30801

亚型

Ig Fraction

Top Product

Discover our top product PSEN2 Primary Antibody
anti-Presenilin 2 (Alzheimer Disease 4) (PSEN2) (N-Term) antibody
PSEN2 适用: 人, 大鼠, 小鼠 WB, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Presenilin 2 (Alzheimer Disease 4) (PSEN2) antibody
PSEN2 适用: 人, 大鼠, 小鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Presenilin 2 (Alzheimer Disease 4) (PSEN2) (AA 39-51), (N-Term) antibody
PSEN2 适用: 人, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Presenilin 2 (Alzheimer Disease 4) (PSEN2) (N-Term) antibody
PSEN2 适用: 人, 大鼠, 小鼠, 犬, Cow, 豚鼠, 马, 兔, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Presenilin 2 (Alzheimer Disease 4) (PSEN2) (AA 33-48), (Intracellular), (N-Term) antibody
PSEN2 适用: 人, 大鼠, 小鼠 WB 宿主: 兔 Polyclonal unconjugated

anti-Presenilin 2 (Alzheimer Disease 4) (PSEN2) (AA 319-334) antibody
PSEN2 适用: 人, 大鼠 WB, IHC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Presenilin 2 (Alzheimer Disease 4) (PSEN2) (AA 101-150) antibody
PSEN2 适用: 人, 大鼠, 小鼠, 犬, Cow, 豚鼠, 马, 兔, 猴, Bat, Hamster, Pig, 小鸡 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Presenilin 2 (Alzheimer Disease 4) (PSEN2) antibody
PSEN2 适用: 人, 大鼠, 小鼠, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Presenilin 2 (Alzheimer Disease 4) (PSEN2) (AA 7-77) antibody
PSEN2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Presenilin 2 (Alzheimer Disease 4) (PSEN2) (AA 32-65) antibody
PSEN2 适用: 人 WB, IHC, IHC (p), FACS 宿主: 兔 Polyclonal unconjugated

应用备注

WB: 1:1000. FC: 1:25

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

有效期

6 months
Levy-Lahad, Poorkaj, Wang, Fu, Oshima, Mulligan, Schellenberg: "Genomic structure and expression of STM2, the chromosome 1 familial Alzheimer disease gene." in: Genomics, Vol. 34, Issue 2, pp. 198-204, (1997) (PubMed).

Li, Ma, Potter: "Identification and expression analysis of a potential familial Alzheimer disease gene on chromosome 1 related to AD3." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 92, Issue 26, pp. 12180-4, (1996) (PubMed).

Levy-Lahad, Wasco, Poorkaj, Romano, Oshima, Pettingell, Yu, Jondro, Schmidt, Wang: "Candidate gene for the chromosome 1 familial Alzheimer's disease locus." in: Science (New York, N.Y.), Vol. 269, Issue 5226, pp. 973-7, (1995) (PubMed).

Rogaev, Sherrington, Rogaeva, Levesque, Ikeda, Liang, Chi, Lin, Holman, Tsuda: "Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene." in: Nature, Vol. 376, Issue 6543, pp. 775-8, (1995) (PubMed).
抗原

Presenilin 2 (PSEN2) (Presenilin 2 (Alzheimer Disease 4) (PSEN2))

别名

PSEN2 (PSEN2 产品)

别名

AD3L antibody, AD4 antibody, CMD1V antibody, PS2 antibody, STM2 antibody, ALG-3 antibody, Ad4h antibody, Alg3 antibody, PS-2 antibody, Psnl2 antibody, pre2 antibody, zf-PS2 antibody, PSNL2 antibody, PSEN2 antibody, ad4 antibody, ps2 antibody, ad3l antibody, stm2 antibody, Ps2 antibody, presenilin 2 antibody, presenilin 2 S homeolog antibody, presenilin 2 (Alzheimer disease 4) antibody, trefoil factor 1 antibody, PSEN2 antibody, Psen2 antibody, psen2 antibody, psen2.S antibody, Tff1 antibody

背景

Probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). Requires the other members of the gamma-secretase complex to have a protease activity. May play a role in intracellular signaling and gene expression or in linking chromatin to the nuclear membrane. May function in the cytoplasmic partitioning of proteins.

分子量

50140

基因ID

5664

UniProt

P49810

途径

Notch Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway