STIM1 抗体 (C-Term)
(2 references)-
- 抗原 See all STIM1 抗体
- STIM1 (Stromal Interaction Molecule 1 (STIM1))
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抗原表位
- C-Term
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适用
- 人, 大鼠, 小鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This STIM1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
- 特异性
- The mouse monoclonal antibody CDN3H4 reacts with a cytoplasmic epitope of human and rodent STIM1, a 84 kDa essential and conserved regulator of store-operated Ca2+ channel function.
- 交叉反应 （详细）
- Human, Mouse, Rat
- 纯化方法
- Purified by protein-A affinity chromatography.
- 纯度
- > 95 % (by SDS-PAGE)
- 免疫原
- Synthetized peptide (C-terminal cytoplasmic part of STIM1).
- 克隆位点
- CDN3H4
- 亚型
- IgG1
- Top Product
- Discover our top product STIM1 Primary Antibody
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anti-Stromal Interaction Molecule 1 (STIM1) (AA 24-685) antibody
STIM1 适用: 人 WB, ELISA, IHC (p), IF 宿主: 小鼠 Monoclonal 5A2 unconjugated
anti-Stromal Interaction Molecule 1 (STIM1) (AA 1-211) antibodySTIM1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Stromal Interaction Molecule 1 (STIM1) (AA 24-686) antibodySTIM1 适用: 人 WB, IHC (p), IF, EIA 宿主: 小鼠 Monoclonal 5A2 unconjugated
anti-Stromal Interaction Molecule 1 (STIM1) (AA 24-686) antibodySTIM1 适用: 人 WB, ELISA, IHC, IHC (p), IF 宿主: 小鼠 Monoclonal 5A2 unconjugated
anti-Stromal Interaction Molecule 1 (STIM1) (AA 56-69), (Extracellular), (N-Term) antibodySTIM1 适用: 人, 大鼠, 小鼠 WB, IHC, IP, IF, ICC, FACS, LCI 宿主: 兔 Polyclonal unconjugated
anti-Stromal Interaction Molecule 1 (STIM1) (C-Term) antibodySTIM1 适用: 人, 大鼠, 小鼠 WB, IHC, IP, IHC (p), ICC, Inhibition 宿主: 小鼠 Monoclonal CDN3H4 unconjugated
anti-Stromal Interaction Molecule 1 (STIM1) (AA 509-538), (C-Term) antibodySTIM1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB19222 unconjugated
anti-Stromal Interaction Molecule 1 (STIM1) (Middle Region) antibodySTIM1 适用: 人, 大鼠, 小鼠, 犬, Cow, 豚鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-Stromal Interaction Molecule 1 (STIM1) (AA 509-538) antibodySTIM1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Stromal Interaction Molecule 1 (STIM1) (C-Term) antibodySTIM1 适用: 人, 大鼠, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Immunocytochemistry: Methanol-aceton fixation, positive control: HeLa human cervix carcinoma cell line.
Immunohistochemistry (paraffin sections): Recommended dilution: 5 μg/mL.
Western blotting: Recommended dilution: 1 μg/mL, positive control: RBL rat basophilic leukemia cell line, both reducing and non-reducing conditions. - 限制
- 仅限研究用
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- 浓度
- 1 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Do not freeze.
- 储存条件
- 4 °C
- 储存方法
- Store at 2-8°C. Do not freeze.
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: "STIM1-directed reorganization of microtubules in activated mast cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 186, Issue 2, pp. 913-23, (2011) (PubMed).
: "Orai1 interacts with STIM1 and mediates capacitative Ca2+ entry in mouse pulmonary arterial smooth muscle cells." in: American journal of physiology. Cell physiology, Vol. 299, Issue 5, pp. C1079-90, (2010) (PubMed).
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: "STIM1-directed reorganization of microtubules in activated mast cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 186, Issue 2, pp. 913-23, (2011) (PubMed).
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- 抗原
- STIM1 (Stromal Interaction Molecule 1 (STIM1))
- 别名
- STIM1 (STIM1 产品)
- 别名
- stim1 antibody, MGC76045 antibody, STIM1 antibody, si:dkey-24p1.5 antibody, MGC154748 antibody, si:ch211-112l17.2 antibody, Stim1 antibody, D11S4896E antibody, GOK antibody, TAM antibody, SIM antibody, stromal interaction molecule 1 antibody, stromal interaction molecule 1a antibody, stromal interaction molecule 1 L homeolog antibody, stromal interaction molecule 1b antibody, STIM1 antibody, stim1 antibody, stim1a antibody, stim1.L antibody, stim1b antibody, Stim1 antibody
- 背景
- Stromal interaction molecule 1,STIM1 (stromal interacting molecule, also known as GOK) acts as a sensor of calcium depletion within the endoplasmic reticulum and transduces the signal to Orai1, the presumptive CRAC channel at the plasma membrane. Following decrease of luminal calcium concentration, STIM1 oligomerizes and induces Orai1 to enable entry of extracellular calcium into the cytoplasm. However, the precise mechanism of STIM1-Orai1 interaction has not been elucidated yet. Many questions also remain to be solved around STIM1 functional distribution. It turns out that STIM1 associates with growing ends of microtubules and is involved in endoplasmic reticulum tubule extension.,GOK, TAM1, STRMK
- 基因ID
- 6786
- UniProt
- G0XQ39
- 途径
- TCR Signaling, BCR Signaling
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