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L-Selectin 抗体 (APC)

Name: L-Selectin 抗体 (APC)
Brand: antibodies-online
SKU: ABIN192344
Availability: OutOfStock

SELL 适用: 人 FACS 宿主: 小鼠 Monoclonal LT-TD180 APC

Flow cytometry surface staining pattern of human peripheral whole blood stained using anti-human CD62L (LT-TD180) APC antibody (10 μL reagent / 100 μL of peripheral whole blood). (L-Selectin 抗体 (APC))

FACS

Surface staining of human peripheral blood cells with anti-CD62L (LT-TD180) Pacific Blue™ (lymphocyte gate). (L-Selectin 抗体 (APC))

FACS

Flow cytometry analysis (surface staining) of human peripheral blood cells with anti-CD62L (LT-TD180) APC. (L-Selectin 抗体 (APC))

FACS

Separation of human CD62L positive lymphocytes (red-filled) from thrombocytes (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood stained using anti-human CD62L (LT-TD180) APC antibody (10 μL reagent / 100 μL of peripheral whole blood). (L-Selectin 抗体 (APC))

FACS

4 images

(4 references)

产品编号 ABIN192344

发货至: 中国

Datasheet as PDF

抗原 See all L-Selectin (SELL) 抗体

L-Selectin (SELL) (Selectin L (SELL))
适用
104

70

34

17

9

6

4

3

2

2

1
人
宿主
80

61

50

1
小鼠
Compatible Secondaries
克隆类型
138

49

3
单克隆
标记
70

28

22

15

13

7

4

4

3

3

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1
This L-Selectin antibody is conjugated to APC
应用范围
142

60

51

45

33

20

17

11

10

9

5

5

4

3

2

2

2

1

1

1

1

1

1

1
Flow Cytometry (FACS)

特异性

The antibody LT-TD180 reacts with an extracellular epitope of CD62L (L-selectin), a 74-95 kDa single chain type I glycoprotein expressed on most peripheral blood B lymphocytes, T lymphocytes, monocytes and granulocytes, it is also present on a subset of NK cells and certain hematopoietic malignant cells.

交叉反应（详细）

Human

纯化方法

Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

免疫原

Peripheral blood leukocytes

克隆位点

LT-TD180

亚型

IgG1

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应用备注

Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 10⁶ cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.

说明

The purified antibody is conjugated with cross-linked Allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.

限制

仅限研究用
溶解方式

No reconstitution is necessary.

缓冲液

Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Do not freeze.
Avoid prolonged exposure to light.

储存条件

4 °C

储存方法

Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Cesana, Santoni de Sio, Rudilosso, Gallina, Calabria, Beretta, Merelli, Bruzzesi, Passerini, Nozza, Vicenzi, Poli, Gregori, Tambussi, Montini: "HIV-1-mediated insertional activation of STAT5B and BACH2 trigger viral reservoir in T regulatory cells." in: Nature communications, Vol. 8, Issue 1, pp. 498, (2017) (PubMed).

Linnebacher, Wienck, Boeck, Klar: "Identification of an MSI-H tumor-specific cytotoxic T cell epitope generated by the (-1) frame of U79260(FTO)." in: Journal of biomedicine & biotechnology, Vol. 2010, pp. 841451, (2010) (PubMed).

Kuttruff, Koch, Kelp, Pawelec, Rammensee, Steinle: "NKp80 defines and stimulates a reactive subset of CD8 T cells." in: Blood, Vol. 113, Issue 2, pp. 358-69, (2009) (PubMed).

Simone, Zicca, Saverino: "The frequency of regulatory CD3+CD8+CD28- CD25+ T lymphocytes in human peripheral blood increases with age." in: Journal of leukocyte biology, Vol. 84, Issue 6, pp. 1454-61, (2008) (PubMed).
抗原

L-Selectin (SELL) (Selectin L (SELL))

别名

CD62L (SELL 产品)

别名

CD62L antibody, LAM1 antibody, LECAM1 antibody, LEU8 antibody, LNHR antibody, LSEL antibody, LYAM1 antibody, PLNHR antibody, TQ1 antibody, A.11 antibody, L-selectin antibody, LECAM-1 antibody, SELE antibody, AI528707 antibody, Lnhr antibody, Ly-22 antibody, Ly-m22 antibody, Lyam-1 antibody, Lyam1 antibody, selectin L antibody, selectin, lymphocyte antibody, SELL antibody, Sell antibody

背景

Selectin L,CD62L (L-selectin) is an adhesion glycoprotein that is constitutively expressed on the cell surface of leukocytes and mediates their homing to inflammatory sites and peripheral lymph nodes by enabling rolling along the venular wall. CD62L is also involved in activation-induced neutrophil aggregation. Activation-dependent CD62L shedding, however, counteracts neutrophil rolling. CD62L has also signaling roles including enhance of chemokine receptor expression. Similarly to CD62P, the major ligand of CD62L is PSGL-1 (P-selectin glycoprotein ligand-1).,L-selectin, LSEL, SELL, LAM-1, LECAM1, LEU8, LNHR, LYAM1, PLNHR

基因ID

6402

UniProt

P14151