(3 references)-
- 抗原 See all CD38 抗体
- CD38
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CD38 antibody is conjugated to APC
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应用范围
- Flow Cytometry (FACS)
- 特异性
- The mouse monoclonal antibody HIT2 reacts with an extracellular epitope of CD38, a 45 kDa type II transmembrane glycoprotein strongly expressed mainly on plasma cells and activated T and B lymphocytes, it is an antigenic marker of lymphoid cells. Its binding is blocked by daratumumab.
- 交叉反应 （详细）
- Human
- 纯化方法
- Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
- 免疫原
- Human thymocytes in foetus
- 克隆位点
- HIT2
- 亚型
- IgG1
- Top Product
- Discover our top product CD38 Primary Antibody
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anti-CD38 (AA 1-300) antibody
适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-CD38 (AA 46-300) antibody适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-CD38 (AA 43-300) antibody适用: 人 WB, IHC, ELISA 宿主: 小鼠 Monoclonal 5C5C3 unconjugated
anti-CD38 (AA 241-270), (C-Term) antibody适用: 人 FACS, WB, IF, IHC (p) 宿主: 兔 Polyclonal RB18001 unconjugated
anti-CD38 (AA 241-270) antibody适用: 人 FACS, WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-CD38 (Internal Region) antibody适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-CD38 antibody适用: 人 FACS, WB, IHC (fro), IHC (p) 宿主: 小鼠 Monoclonal HIT2 unconjugated
anti-CD38 antibody (PE)适用: 人 FACS 宿主: 小鼠 Monoclonal HIT2 PE
anti-CD38 antibody (PE-DyLight 594)适用: 人 FACS 宿主: 小鼠 Monoclonal HIT2 PE-DyLight 594
anti-CD38 (AA 101-200) antibody适用: 小鼠, 大鼠 FACS, WB, ELISA, IHC (fro), IHC (p), IF (p), IF (cc) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
- 说明
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The purified antibody is conjugated with cross-linked Allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.
- 限制
- 仅限研究用
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- 溶解方式
- No reconstitution is necessary.
- 缓冲液
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
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Do not freeze.
Avoid prolonged exposure to light. - 储存条件
- 4 °C
- 储存方法
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
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: "Analysis of B-cell subpopulations in monoclonal gammopathies." in: Clinical lymphoma, myeloma & leukemia, Vol. 15, Issue 4, pp. e61-71, (2015) (PubMed).
: "Toll-like receptors on B-CLL cells: expression and functional consequences of their stimulation." in: International journal of cancer. Journal international du cancer, Vol. 126, Issue 5, pp. 1132-43, (2010) (PubMed).
: "A novel human B cell subpopulation representing the initial germinal center population to express AID." in: Blood, Vol. 109, Issue 6, pp. 2545-52, (2007) (PubMed).
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: "Analysis of B-cell subpopulations in monoclonal gammopathies." in: Clinical lymphoma, myeloma & leukemia, Vol. 15, Issue 4, pp. e61-71, (2015) (PubMed).
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- 抗原
- CD38
- Abstract
- CD38 产品
- 别名
- T10 antibody, Cd38-rs1 antibody, cd38 antibody, ADPRC 1 antibody, cADPr hydrolase 1 antibody, CD38 molecule antibody, CD38 antigen antibody, CD38 molecule L homeolog antibody, ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 antibody, CD38 antibody, Cd38 antibody, cd38.L antibody
- 背景
- CD38 Molecule,CD38 (NAD+ glycohydrolase) is a type II transmembrane glycoprotein able to induce activation, proliferation and differentiation of mature lymphocytes and mediate apoptosis of myeloid and lymphoid progenitor cells. Another role of CD38 is provided by enzymatic activity of its extracellular part. CD38 acts as NAD+ glycohydrolase converting NAD+ into ADP-ribose, as ADP-ribosyl cyclase producing cADPR and as cADPR hydrolase, thus affecting levels of calcium-mobilizing metabolites. ADPR produced by CD38 serves as an important second messenger of neutrophil and dendritic cell migration.,ADPRC1, cADPr hydrolase 1, T10, NAD(+) nucleosidase, ADP-ribosyl cyclase 1
- 基因ID
- 952
- UniProt
- P28907
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