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Laminin 5 抗体

LN-5 适用: 人, 大鼠 WB, IHC (fro), EIA 宿主: 小鼠 Monoclonal 6F12 unconjugated
产品编号 ABIN191945
发货至: 中国
  • 抗原 See all Laminin 5 (LN-5) products
    Laminin 5 (LN-5)
    适用
    • 9
    • 1
    • 1
    • 1
    人, 大鼠
    宿主
    • 5
    • 4
    小鼠
    克隆类型
    • 5
    • 4
    单克隆
    标记
    • 9
    This Laminin 5 antibody is un-conjugated
    应用范围
    • 8
    • 6
    • 5
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)
    产品特性
    Synonyms: Laminin-5
    纯化方法
    Protein A Chromatography
    免疫原
    Human Laminin 5 beta 3 chain
    克隆位点
    6F12
    亚型
    IgG
  • 应用备注
    Western blot. ELISA (coating antibody in Sandwich ELISA). Immunohistochemistry on Cryosections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 溶解方式
    Restore in aqua bidest to initial volume.
    缓冲液
    PBS, pH 7.4
    储存条件
    4 °C/-20 °C
    储存方法
    Store lyophilized at 2-8 °C and reconstituted at -20 °C. Avoid repeated freezing and thawing.
    Shelf life: One year from despatch.
    有效期
    12 months
  • Drumea-Mirancea, Wessels, Müller, Essl, Eble, Tolosa, Koch, Reinhardt, Sixt, Sorokin, Stierhof, Schwarz, Klein: "Characterization of a conduit system containing laminin-5 in the human thymus: a potential transport system for small molecules." in: Journal of cell science, Vol. 119, Issue Pt 7, pp. 1396-405, (2006) (PubMed).

    Amano, Akutsu, Ogura, Nishiyama: "Increase of laminin 5 synthesis in human keratinocytes by acute wound fluid, inflammatory cytokines and growth factors, and lysophospholipids." in: The British journal of dermatology, Vol. 151, Issue 5, pp. 961-70, (2004) (PubMed).

    Sasaki, Amano, Nishiyama, Nakayama, Burgeson, Nakajima: "Expression of laminin 5, and collagen IV and VII in bullous pemphigoid skin." in: Archives of dermatological research, Vol. 290, Issue 5, pp. 283-5, (1998) (PubMed).

    Barnstable, Bodmer, Brown, Galfre, Milstein, Williams, Ziegler: "Production of monoclonal antibodies to group A erythrocytes, HLA and other human cell surface antigens-new tools for genetic analysis." in: Cell, Vol. 14, Issue 1, pp. 9-20, (1978) (PubMed).

  • 抗原
    Laminin 5 (LN-5)
    别名
    Laminin 5 (LN-5 产品)
    背景
    Laminins are basement membrane components thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. laminin 5 is a complex glycoprotein composed of three subunits (alpha, beta, and gamma). Laminin 5 is thought to be involved in cell adhesion, signal transduction and differentiation of keratinocytes. Mutations in this gene have been identified as the cause of Herlitz type junctional epidermolysis bullosa. Alternatively spliced transcript variants encoding different isoforms have been identified.Synonyms: Laminin-5
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