WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
注意事项
Avoid freezing and thawing repeatly.
储存条件
4 °C/-20 °C
储存方法
Store at 4 °C for short term use.Store at -20 °C for long term preservation.
抗原
DNAJC13
(DnaJ heat shock protein family (Hsp40) member C13 (DNAJC13))
RME8 antibody, D030002L11Rik antibody, Gm1124 antibody, RME-8 antibody, Rme8 antibody, mKIAA0678 antibody, DnaJ heat shock protein family (Hsp40) member C13 antibody, dnaJ homolog subfamily C member 13 antibody, DNAJC13 antibody, LOC100167963 antibody, LOC100640734 antibody, Dnajc13 antibody
背景
DNAJC13, also known as receptor-mediated endocytosis 8 (RME8), is the human homolog to a DnaJ domain-containing protein originally identified in a screen for endocytic defects in C.elegans.It is thought to be a co-chaperone of Hsc70 which regulates protein conformation at membrane sites and plays a role in intracellular trafficking, co-localizing with markers of the endosomal system.Recent experiments have indicated that the DNAJC13 protein is involved in membrane trafficking through early endosomes but not through degradative organelles.DNAJC13 has been also been shown to regulate the intracellular trafficking of the epidermal growth factor receptor. Synonyms: DNAJ homolog subfamily C member 13, receptor-mediated endocytosis 8, RME8