At least two isoforms of B9D1 are known to exist, this antibody will only recognize the longest isoform. B9D1 antibody is predicted to not cross-react with other DNAJC family members.
纯化方法
Affinity chromatography purified via peptide column
免疫原
B9D1 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human B9D1.
WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
注意事项
Avoid freezing and thawing repeatly.
储存条件
4 °C/-20 °C
储存方法
Store at 4 °C for short term use.Store at -20 °C for long term preservation.
Meckel syndrome (MKS) is an embryonic lethal, autosomal recessive disorder characterized by polycystic kidney disease, central nervous system defects, polydactyly and liver fibrosis.B9D1 is a B9 domain-containing protein, one of several that are involved in ciliogenesis.Alterations in expression of this gene have been found in a family with Meckel syndrome.B9D1, and its related protein B9D2, form a complex with MKS1, disruption of which causes MKS.B9D1 is thought to be required for normal hedgehog signaling, ciliogenesis, and ciliary protein localization . Synonyms: B9 domain-containing protein 1, B9, MKS9, EPPB9, MKSR1