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IL22R 抗体 (AA 560-574)

IL22R 适用: 人, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1886889
发货至: 中国
  • 抗原 See all IL22R products
    IL22R (Interleukin 22 Receptor (IL22R))
    抗原表位
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 560-574
    适用
    • 9
    • 3
    • 2
    人, 大鼠
    宿主
    • 10
    • 2
    克隆类型
    • 12
    多克隆
    标记
    • 11
    • 1
    This IL22R antibody is un-conjugated
    应用范围
    • 10
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    Synthetic peptide corresponding to amino acids 560 to 574 of human IL-22 receptor precursor.
  • 限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
    注意事项
    Avoid freezing and thawing repeatly.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 4 °C for short term use.Store at -20 °C for long term preservation.
  • 抗原
    IL22R (Interleukin 22 Receptor (IL22R))
    Abstract
    IL22R 产品
    背景
    A novel cytokine, designated IL-TIF for IL-10 related T cell-derived inducible factor and IL-22, was recently identified.The receptor for IL-22 (IL-22R, also termed CRF2-9 and IL-TIF-R1 chain) is a new member of the class II cytokine receptor family.IL-22R forms a complex with IL-10 receptor beta chain and mediates IL-22 signaling.IL-22 and its receptor activate JAK-STAT signaling pathway.IL22R is expressed in normal liver and kidney and their cell lines HepG2 and TK-10.A soluble form of IL-22 receptor, also termed IL-22 binding protein (IL-22BP) and IL-22 receptor-alpha 2 (IL-22RA2), was identified very recently.IL-22BP prevents binding of IL-22 to the functional cell surface IL-22R complex and neutralizes IL-22 activity.LPS induces IL-22 expression, which indicates the role of IL-22 in inflammatory response.
    Synonyms: IL22R
    分子量
    62 kDa
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