UCHL1 抗体
-
- 抗原 See all UCHL1 抗体
- UCHL1 (Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1))
-
适用
- 人, 大鼠
-
宿主
- 小鼠
-
克隆类型
- 单克隆
-
标记
- This UCHL1 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 预测反应
- B, Hs, Pr, M, Pig
- 纯化方法
- This antibody is purified through a protein G column, followed by dialysis against PBS.
- 免疫原
- This UCHL1 Monoclonal antibody is generated from mouses immunized with a KLH conjugated synthetic peptide selected from the 185-214 region of human UCHL1.
- 克隆位点
- 696CT2-1-4
- 亚型
- IgG1
- Top Product
- Discover our top product UCHL1 Primary Antibody
-
-
- 应用备注
- WB: 1:1000. IHC-P: 1:25. IHC-P: 1:25
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 缓冲液
- Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 有效期
- 6 months
-
-
Ubiquitin vinyl methyl ester binding orients the misaligned active site of the ubiquitin hydrolase UCHL1 into productive conformation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 20, pp. 9117-22, (2010) (PubMed).
: "Generation and annotation of the DNA sequences of human chromosomes 2 and 4. ..." in: Nature, Vol. 434, Issue 7034, pp. 724-31, (2005) (PubMed).
: "Oxidative modifications and down-regulation of ubiquitin carboxyl-terminal hydrolase L1 associated with idiopathic Parkinson's and Alzheimer's diseases." in: The Journal of biological chemistry, Vol. 279, Issue 13, pp. 13256-64, (2004) (PubMed).
: "The structure of the human gene encoding protein gene product 9.5 (PGP9.5), a neuron-specific ubiquitin C-terminal hydrolase." in: The Biochemical journal, Vol. 268, Issue 2, pp. 521-4, (1990) (PubMed).
: "
-
Ubiquitin vinyl methyl ester binding orients the misaligned active site of the ubiquitin hydrolase UCHL1 into productive conformation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 20, pp. 9117-22, (2010) (PubMed).
-
- 抗原
- UCHL1 (Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1))
- 别名
- UCHL1 (UCHL1 产品)
- 背景
- Ubiquitin-protein hydrolase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. Also binds to free monoubiquitin and may prevent its degradation in lysosomes. The homodimer may have ATP-independent ubiquitin ligase activity.
- 分子量
- 24824
- NCBI登录号
- NP_004172
- UniProt
- P09936
- 途径
- Feeding Behaviour
-