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LEF1 抗体 (AA 10-37)

Name: LEF1 抗体 (AA 10-37)
SKU: ABIN1882259
Availability: OutOfStock

LEF1 适用: 人 WB 宿主: 小鼠 Monoclonal 661CT8-3-5 unconjugated

LEF1 Antibody ABIN1882259 western blot analysis in K562 cell line lysates (35 μg/lane). (LEF1 抗体 (AA 10-37))

1 image

(3 references)

产品编号 ABIN1882259

发货至: 中国

Datasheet as PDF

抗原 See all LEF1 抗体

LEF1 (Lymphoid Enhancer-Binding Factor 1 (LEF1))
抗原表位
10

8

7

6

5

4

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 10-37
适用
77

19

13

7

7

6

4

4

4

4

3

3

2

1

1
人
宿主
50

22

4

1
小鼠
Compatible Secondaries
克隆类型
54

23
单克隆
标记
57

4

3

3

2

2

1

1

1

1

1

1
This LEF1 antibody is un-conjugated
应用范围
64

35

12

9

5

5

4

2

2

2

2

1

1

1
Western Blotting (WB)

预测反应

M, Rat

纯化方法

Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.

免疫原

This LEF1 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 10-37 amino acids from human LEF1.

克隆位点

661CT8-3-5

亚型

IgG1

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LEF1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Lymphoid Enhancer-Binding Factor 1 (LEF1) (AA 1-399) antibody
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anti-Lymphoid Enhancer-Binding Factor 1 (LEF1) (Internal Region) antibody
Verified LEF1 适用: 人 WB, ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated

anti-Lymphoid Enhancer-Binding Factor 1 (LEF1) (AA 33-138) antibody
LEF1 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 1A4B11 unconjugated

anti-Lymphoid Enhancer-Binding Factor 1 (LEF1) (AA 14-123) antibody
LEF1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 5A3 unconjugated

anti-Lymphoid Enhancer-Binding Factor 1 (LEF1) (AA 75-216) antibody
LEF1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Lymphoid Enhancer-Binding Factor 1 (LEF1) (AA 33-138) antibody
LEF1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1A8 unconjugated

anti-Lymphoid Enhancer-Binding Factor 1 (LEF1) (AA 10-37), (N-Term) antibody
LEF1 适用: 人 WB, IF 宿主: 兔 Polyclonal RB31989 unconjugated

anti-Lymphoid Enhancer-Binding Factor 1 (LEF1) (Internal Region) antibody
LEF1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

WB: 1:500~8000

限制

仅限研究用
状态

Liquid

缓冲液

Mouse monoclonal antibody supplied in crude ascites with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

有效期

6 months
Gutierrez, Tschumper, Wu, Shanafelt, Eckel-Passow, Huddleston, Slager, Kay, Jelinek: "LEF-1 is a prosurvival factor in chronic lymphocytic leukemia and is expressed in the preleukemic state of monoclonal B-cell lymphocytosis." in: Blood, Vol. 116, Issue 16, pp. 2975-83, (2010) (PubMed).

Kalsi, Kuo, Aliev, Alexander, McMichael, Patterson, Walsh, Zhao, Schuckit, Nurnberger, Edenberg, Kramer, Hesselbrock, Tischfield, Vladimirov, Prescott, Dick, Kendler, Riley: "A systematic gene-based screen of chr4q22-q32 identifies association of a novel susceptibility gene, DKK2, with the quantitative trait of alcohol dependence symptom counts." in: Human molecular genetics, Vol. 19, Issue 12, pp. 2497-506, (2010) (PubMed).

Chen, Zhang, Pincus, Wu, Ricks, Liu, Sun, Maclaren, Lan: "Human CD1D gene expression is regulated by LEF-1 through distal promoter regulatory elements." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 184, Issue 9, pp. 5047-54, (2010) (PubMed).
抗原

LEF1 (Lymphoid Enhancer-Binding Factor 1 (LEF1))

别名

LEF1 (LEF1 产品)

别名

LEF1 antibody, 3000002B05 antibody, AI451430 antibody, Lef-1 antibody, LEF-1 antibody, TCF10 antibody, TCF1ALPHA antibody, TCF7L3 antibody, lymphoid enhancer binding factor 1 antibody, lymphoid enhancer-binding factor 1 antibody, lymphoid enhancer factor XLEF-1B antibody, LEF1 antibody, lef1 antibody, Lef1 antibody

背景

This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants.

分子量

44201

NCBI登录号

NP_001124185, NP_001124186, NP_001159591, NP_057353

UniProt

Q9UJU2

途径

WNT signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Hormone Metabolic Process, Nuclear Hormone Receptor Binding, Chromatin Binding