电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

Filamin A 抗体 (AA 1-360)

FLNA 适用: 人, 小鼠, 大鼠 WB 宿主: 小鼠 Monoclonal 1273CT424-104-153 unconjugated
产品编号 ABIN1882243
发货至: 中国
  • 抗原 See all Filamin A (FLNA) 抗体
    Filamin A (FLNA) (Filamin A, alpha (FLNA))
    抗原表位
    • 15
    • 15
    • 13
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-360
    适用
    • 98
    • 25
    • 20
    • 3
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 91
    • 6
    • 1
    小鼠
    克隆类型
    • 81
    • 17
    单克隆
    标记
    • 46
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This Filamin A antibody is un-conjugated
    应用范围
    • 53
    • 33
    • 28
    • 28
    • 28
    • 26
    • 13
    • 11
    • 7
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB)
    纯化方法
    This antibody is purified through a protein G column, followed by dialysis against PBS.
    免疫原
    Purified His-tagged FLNA protein was used to produced this monoclonal antibody.
    克隆位点
    1273CT424-104-153
    亚型
    IgG1
    Top Product
    Discover our top product FLNA Primary Antibody
  • 应用备注
    WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • Campos, Rodriguez, Machado Leopoldino, Hait, Lopez Bergami, Castro, Sanchez, Maceyka, Spiegel, Alvarez: "Filamin A Expression Negatively Regulates Sphingosine-1-Phosphate-Induced NF-?B Activation in Melanoma Cells by Inhibition of Akt Signaling." in: Molecular and cellular biology, (2015) (PubMed).

    Li, Liu, Wang, Liu, Liu, Li, Wan, Wang, Zhang, Jin, Liu, Zhu, Liu: "Systematic mapping and functional analysis of a family of human epididymal secretory sperm-located proteins." in: Molecular & cellular proteomics : MCP, Vol. 9, Issue 11, pp. 2517-28, (2010) (PubMed).

    Chen, Zollo, Mazzarella, Ciccodicola, Chen, Zuo, Heiner, Burough, Repetto, Schlessinger, DUrso: "Long-range sequence analysis in Xq28: thirteen known and six candidate genes in 219.4 kb of high GC DNA between the RCP/GCP and G6PD loci." in: Human molecular genetics, Vol. 5, Issue 5, pp. 659-68, (1997) (PubMed).

    Patrosso, Repetto, Villa, Milanesi, Frattini, Faranda, Mancini, Maestrini, Toniolo, Vezzoni: "The exon-intron organization of the human X-linked gene (FLN1) encoding actin-binding protein 280." in: Genomics, Vol. 21, Issue 1, pp. 71-6, (1994) (PubMed).

    Gorlin, Yamin, Egan, Stewart, Stossel, Kwiatkowski, Hartwig: "Human endothelial actin-binding protein (ABP-280, nonmuscle filamin): a molecular leaf spring." in: The Journal of cell biology, Vol. 111, Issue 3, pp. 1089-105, (1990) (PubMed).

  • 抗原
    Filamin A (FLNA) (Filamin A, alpha (FLNA))
    别名
    FLNA (FLNA 产品)
    背景
    Promotes orthogonal branching of actin filaments and links actin filaments to membrane glycoproteins. Anchors various transmembrane proteins to the actin cytoskeleton and serves as a scaffold for a wide range of cytoplasmic signaling proteins. Interaction with FLNA may allow neuroblast migration from the ventricular zone into the cortical plate. Tethers cell surface-localized furin, modulates its rate of internalization and directs its intracellular trafficking (By similarity). Involved in ciliogenesis.
    分子量
    280739
    NCBI登录号
    NP_001104026, NP_001447
    UniProt
    P21333
    途径
    TCR Signaling, Maintenance of Protein Location
You are here:
客服