我们推荐在您的浏览器上开启Javascript，以获得最佳效果。

COMT 抗体 (N-Term)

Name: COMT 抗体 (N-Term)
SKU: ABIN1882224
Availability: OutOfStock

COMT 适用: 人 WB 宿主: 小鼠 Monoclonal 630CT1-7-1 unconjugated

COMT Antibody (N-term)(Ascites) ABIN1882224 western blot analysis in Hela cell line lysates (35 μg/lane). (COMT 抗体 (N-Term))

1 image

(5 references)

产品编号 ABIN1882224

发货至: 中国

Datasheet as PDF

抗原 See all COMT 抗体

COMT (Catechol-O-Methyltransferase (COMT))
抗原表位
15

5

4

4

3

3

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1
AA 37-65, N-Term
适用
53

36

35

5

3

3

2

2

2

1

1
人
宿主
64

6

3

1
小鼠
Compatible Secondaries
克隆类型
62

12
单克隆
标记
42

5

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1
This COMT antibody is un-conjugated
应用范围
39

23

16

13

13

11

9

7

7

4

3

3

2

1
Western Blotting (WB)

纯化方法

Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.

免疫原

This COMT antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 37-65 amino acids from the N-terminal region of human COMT.

克隆位点

630CT1-7-1

亚型

IgG1

Top Product

Discover our top product COMT Primary Antibody
anti-Catechol-O-Methyltransferase (COMT) (Internal Region) antibody
Verified COMT 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated

anti-Catechol-O-Methyltransferase (COMT) (N-Term) antibody
Verified COMT 适用: 人 WB, ELISA, FACS 宿主: 山羊 Polyclonal unconjugated

anti-Catechol-O-Methyltransferase (COMT) antibody
KO Validated COMT 适用: 人 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Catechol-O-Methyltransferase (COMT) (AA 52-271) antibody
COMT 适用: 人, 小鼠, 大鼠 WB, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated

anti-Catechol-O-Methyltransferase (COMT) (AA 1-182) antibody
COMT 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1G4-1A1 unconjugated

anti-Catechol-O-Methyltransferase (COMT) (AA 52-271) antibody
COMT 适用: 人 WB, ELISA, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Catechol-O-Methyltransferase (COMT) (AA 1-221) antibody
COMT 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated

anti-Catechol-O-Methyltransferase (COMT) (AA 1-221) antibody
COMT 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated

anti-Catechol-O-Methyltransferase (COMT) (Internal Region) antibody
COMT 适用: 人, 小鼠, 大鼠, 猴, Pig, Cow, Bat IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Catechol-O-Methyltransferase (COMT) (C-Term) antibody
COMT 适用: 人 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

应用备注

WB: 1:100~400

限制

仅限研究用
状态

Liquid

缓冲液

Mouse monoclonal antibody supplied in crude ascites with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

有效期

6 months
Zeng, Ye, Lu, Chua, Tan, Zhong: "Chiral Brønsted acid catalyzed enantioselective addition of alpha-isocyanoacetamides to aldehydes." in: Organic letters, Vol. 12, Issue 10, pp. 2414-7, (2010) (PubMed).

Stroth, Reinhardt, Thöne, Hille, Schneider, Härtel, Weidemann, Bös, Spitzer: "Impact of aerobic exercise training on cognitive functions and affect associated to the COMT polymorphism in young adults." in: Neurobiology of learning and memory, Vol. 94, Issue 3, pp. 364-72, (2010) (PubMed).

Lim, Kim, Kim, Park, Han, Han, Lee, Yang, Ryu: "Genetic polymorphism of catechol-O-methyltransferase and cytochrome P450c17α in preeclampsia." in: Pharmacogenetics and genomics, Vol. 20, Issue 10, pp. 605-10, (2010) (PubMed).

Demetrovics, Varga, Szekely, Vereczkei, Csorba, Balazs, Hoffman, Sasvari-Szekely, Barta: "Association between Novelty Seeking of opiate-dependent patients and the catechol-O-methyltransferase Val(158)Met polymorphism." in: Comprehensive psychiatry, Vol. 51, Issue 5, pp. 510-5, (2010) (PubMed).

Bodenmann, Landolt: "Effects of modafinil on the sleep EEG depend on Val158Met genotype of COMT." in: Sleep, Vol. 33, Issue 8, pp. 1027-35, (2010) (PubMed).
抗原

COMT (Catechol-O-Methyltransferase (COMT))

别名

COMT (COMT 产品)

别名

Comt1 antibody, D16Wsu103e antibody, D330014B15Rik antibody, COMT antibody, mb-comt antibody, s-comt antibody, comt antibody, MGC154444 antibody, zgc:114157 antibody, si:dkey-13a21.15 antibody, zK13A21.15 antibody, zgc:162236 antibody, catechol-O-methyltransferase antibody, microRNA 4761 antibody, catechol-O-methyltransferase S homeolog antibody, methyltransferase antibody, catechol-o-methyltransferase antibody, catechol-O-methyltransferase a antibody, catechol-O-methyltransferase b antibody, catechol O-methyltransferase antibody, COMT antibody, Comt antibody, MIR4761 antibody, comt antibody, comt.2 antibody, comt.S antibody, Rv1703c antibody, Mb1729c antibody, comta antibody, comtb antibody, LOC100354142 antibody

背景

Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease. COMT is found in two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT). The differences between S-COMT and MB-COMT reside within the N-termini. Several transcript variants are formed through the use of alternative translation initiation sites and promoters.

分子量

30037

NCBI登录号

NP_000745, NP_001128633, NP_001128634, NP_009294

UniProt

P21964

途径

Steroid Hormone Biosynthesis, SARS-CoV-2 Protein Interactome