-
- 抗原 See all AGT 抗体
- AGT (Angiotensinogen (serpin Peptidase Inhibitor, Clade A, Member 8) (AGT))
-
抗原表位
- AA 37-65, N-Term
-
适用
- 人
-
宿主
- 小鼠
-
克隆类型
- 单克隆
-
标记
- This AGT antibody is un-conjugated
-
应用范围
- Western Blotting (WB)
- 纯化方法
- This antibody is purified through a protein G column, followed by dialysis against PBS.
- 免疫原
- This AGT antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 37-65 amino acids from the N-terminal region of human AGT.
- 克隆位点
- 656CT5-8-4
- 亚型
- IgG1
- Top Product
- Discover our top product AGT Primary Antibody
-
-
- 应用备注
- WB: 1:100~1000
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 缓冲液
- Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 有效期
- 6 months
-
-
Renin-angiotensin system gene polymorphisms in children with Henoch-Schönlein purpura in West China." in: Journal of the renin-angiotensin-aldosterone system : JRAAS, Vol. 11, Issue 4, pp. 248-55, (2010) (PubMed).
: "[Role of the M235T (c.704c>T) polymorphism of angiotensynogen gene as well as A724A (c.2171G>A) polymorphism of SERCA2a gene in ethiopathogenesis of left ventricular hypertrophy in essential..." in: Przegla̧d lekarski, Vol. 67, Issue 3, pp. 151-6, (2010) (PubMed).
: "Renin angiotensin system polymorphisms in patients with metabolic syndrome (MetS)." in: European journal of internal medicine, Vol. 21, Issue 5, pp. 414-8, (2010) (PubMed).
: "
-
Renin-angiotensin system gene polymorphisms in children with Henoch-Schönlein purpura in West China." in: Journal of the renin-angiotensin-aldosterone system : JRAAS, Vol. 11, Issue 4, pp. 248-55, (2010) (PubMed).
-
- 抗原
- AGT (Angiotensinogen (serpin Peptidase Inhibitor, Clade A, Member 8) (AGT))
- 别名
- AGT (AGT 产品)
- 别名
- ANHU antibody, SERPINA8 antibody, AI265500 antibody, AngI antibody, AngII antibody, Aogen antibody, Serpina8 antibody, ANRT antibody, Ang antibody, PAT antibody, wu:fb62f06 antibody, wu:fj87b02 antibody, zgc:111892 antibody, AGT antibody, angt antibody, ANGT antibody, angiotensinogen antibody, angiotensinogen (serpin peptidase inhibitor, clade A, member 8) antibody, AGT antibody, Agt antibody, agt antibody
- 背景
- The protein encoded by this gene, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease.
- 分子量
- 53154
- NCBI登录号
- NP_000020
- UniProt
- P01019
- 途径
- JAK/STAT Signaling, ACE Inhibitor Pathway, EGFR Signaling Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Regulation of Lipid Metabolism by PPARalpha, Protein targeting to Nucleus, Feeding Behaviour, Monocarboxylic Acid Catabolic Process, Dicarboxylic Acid Transport, Positive Regulation of Response to DNA Damage Stimulus, Regulation of long-term Neuronal Synaptic Plasticity
-