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- 抗原 See all KIT 抗体
- KIT (Mast/stem Cell Growth Factor Receptor (KIT))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This KIT antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- This antibody is prepared by Euglobin precipitation followed by dialysis against PBS.
- 免疫原
- This KIT Antibody is generated from mouses immunized with human KIT recombinant protein.
- 克隆位点
- 566CT8-5-4
- 亚型
- IgM
- Top Product
- Discover our top product KIT Primary Antibody
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- 应用备注
- IF: 1:100. IF: 1:10~50. WB: 1:100. IHC-P-Leica: 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 有效期
- 6 months
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Comparative analysis of mutation of tyrosine kinase kit in mast cells from patients with systemic mast cell activation syndrome and healthy subjects." in: Immunogenetics, Vol. 62, Issue 11-12, pp. 721-7, (2010) (PubMed).
: "CXCR4-mediated bone marrow progenitor cell maintenance and mobilization are modulated by c-kit activity." in: Circulation research, Vol. 107, Issue 9, pp. 1083-93, (2010) (PubMed).
: "ETV1 is a lineage survival factor that cooperates with KIT in gastrointestinal stromal tumours." in: Nature, Vol. 467, Issue 7317, pp. 849-53, (2010) (PubMed).
: "Molecular and clinicopathologic characterization of gastrointestinal stromal tumors (GISTs) of small size." in: The American journal of surgical pathology, Vol. 34, Issue 10, pp. 1480-91, (2010) (PubMed).
: "Efficacy evaluation of imatinib treatment in patients with gastrointestinal stromal tumors: a meta-analysis." in: World journal of gastroenterology : WJG, Vol. 16, Issue 33, pp. 4227-32, (2010) (PubMed).
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Comparative analysis of mutation of tyrosine kinase kit in mast cells from patients with systemic mast cell activation syndrome and healthy subjects." in: Immunogenetics, Vol. 62, Issue 11-12, pp. 721-7, (2010) (PubMed).
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- 抗原
- KIT (Mast/stem Cell Growth Factor Receptor (KIT))
- 别名
- KIT (KIT 产品)
- 别名
- C-Kit antibody, CD117 antibody, PBT antibody, SCFR antibody, Bs antibody, Fdc antibody, Gsfsco1 antibody, Gsfsco5 antibody, Gsfsow3 antibody, SCO1 antibody, SCO5 antibody, SOW3 antibody, Ssm antibody, Tr-kit antibody, W antibody, c-KIT antibody, c-kit antibody, MGF antibody, KIT antibody, C-KIT antibody, kit antibody, receptor antibody, sparse antibody, Xkl-1 antibody, kit-a antibody, kit-b antibody, kl1-A antibody, krk1 antibody, pbt antibody, scfr antibody, KIT proto-oncogene receptor tyrosine kinase antibody, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog a antibody, KIT proto-oncogene receptor tyrosine kinase S homeolog antibody, KIT antibody, Kit antibody, kita antibody, kit antibody, kit.S antibody
- 背景
- This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene.
- 分子量
- 109865
- NCBI登录号
- NP_000213, NP_001087241
- UniProt
- P10721
- 途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Sensory Perception of Sound, Stem Cell Maintenance, Production of Molecular Mediator of Immune Response, Regulation of long-term Neuronal Synaptic Plasticity
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