-
- 抗原 See all DUSP6 抗体
- DUSP6 (Dual Specificity Phosphatase 6 (DUSP6))
-
适用
- 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This DUSP6 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Flow Cytometry (FACS)
- 纯化方法
- This antibody is purified through a protein A column, followed by dialysis against PBS.
- 免疫原
- This Rat MKP3 antibody is generated from rabbits immunized with a 6xHIS-tagged recombinant protein encoding aa 1~381 of rat MKP3.
- 克隆位点
- RB7281
- 亚型
- Ig Fraction
- Top Product
- Discover our top product DUSP6 Primary Antibody
-
-
- 应用备注
- WB: 1:1000. FC: 1:10~50
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 缓冲液
- Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 有效期
- 6 months
-
-
Mitogen-activated protein kinase activation and regulation in the pressure-loaded fetal ovine heart." in: American journal of physiology. Heart and circulatory physiology, Vol. 290, Issue 4, pp. H1587-95, (2006) (PubMed).
: "MKP-3, a novel cytosolic protein-tyrosine phosphatase that exemplifies a new class of mitogen-activated protein kinase phosphatase." in: The Journal of biological chemistry, Vol. 271, Issue 8, pp. 4319-26, (1996) (PubMed).
: "A novel cytoplasmic dual specificity protein tyrosine phosphatase implicated in muscle and neuronal differentiation." in: The Journal of biological chemistry, Vol. 271, Issue 7, pp. 3795-802, (1996) (PubMed).
: "
-
Mitogen-activated protein kinase activation and regulation in the pressure-loaded fetal ovine heart." in: American journal of physiology. Heart and circulatory physiology, Vol. 290, Issue 4, pp. H1587-95, (2006) (PubMed).
-
- 抗原
- DUSP6 (Dual Specificity Phosphatase 6 (DUSP6))
- 别名
- MKP3 (DUSP6 产品)
- 别名
- HH19 antibody, MKP3 antibody, PYST1 antibody, 1300019I03Rik antibody, MKP-3 antibody, Mkp3 antibody, wu:fd99d09 antibody, mkp3 antibody, pyst1 antibody, DUSP6 antibody, dusp6 antibody, dual specificity phosphatase 6 antibody, dual specificity phosphatase 6 L homeolog antibody, Dual specificity protein phosphatase 6 antibody, DUSP6 antibody, Dusp6 antibody, dusp6 antibody, dusp6.L antibody, dus6 antibody
- 背景
- Dual specificity protein tyrosine phosphatases (dsPTPs) are a subfamily of protein tyrosine phosphatases implicated in the regulation of mitogen-activated protein kinase (MAPK). MKP-1 (also known as CL100, 3CH134, Erp, and hVH-1) exemplifies a class of dual-specificity phosphatase able to reverse the activation of MAP kinases by dephosphorylating critical tyrosine and threonine residues. MKP-3 is 36 % identical to MKP-1 and it blocks both the phosphorylation and enzymatic activation of ERK2 by mitogens. MKP-3 mRNA is expressed in lung, heart, brain, and kidney, but not significantly in skeletal muscle or testis
- 分子量
- 42319
- NCBI登录号
- NP_446335
- UniProt
- Q64346
- 途径
- Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
-